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Prevalence of Renal Artery Stenosis in Patients Referred for Cardiac Catheterization (RAS)

This study has been completed.
Sponsor:
Collaborator:
Tehran Heart Center
Information provided by:
Imam Khomeini Hospital
ClinicalTrials.gov Identifier:
NCT00885768
First received: July 11, 2008
Last updated: May 11, 2011
Last verified: April 2009
History of Changes
  Purpose

All patients referred for coronary angiography will simultaneously be evaluated for renal artery stenosis and then stenosis more than 50% will be analyzed according to clinical conditions, risk factors and lab data.


Condition Intervention Phase
Renal Artery Stenosis
 Procedure: angiography
 Phase 3

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Prevalence of Renal Artery Stenosis in Patients Refered for Cardiac Catheterization to Heart Center Hospital in July-September 2008

Further study details as provided by Imam Khomeini Hospital:

Primary Outcome Measures:
  • Prevalence of Renal Artery Stenosis (RAS) [ Time Frame: 2 months ] [ Designated as safety issue: Yes ]
  • The Number of Patients With Renal Artery Stenosis [ Time Frame: 3months ] [ Designated as safety issue: Yes ]
    the prevalence of renal artery stenosis in patients with coronary artery disease


Enrollment: 146
Study Start Date: July 2008
Study Completion Date: April 2009
Primary Completion Date: September 2008 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
A
patients with renal artery stenosis
 Procedure: angiography
all patients undergoing coronary angiography with VISIPAQUE and if they had coronary stenosis then renal artery angiography will be done. the dose of contrast will be chosen according to renal function and clinical conditions which will be varied from 75 to 300 ml.

Detailed Description:

Renal Artery Stenosis (RAS) is a common finding in patients with generalized atherosclerosis. It is the cause of 15-20% of end stage renal disease in elderly patients. The prevalence of asymptomatic RAS in general population is unknown but it estimated to be 18% in 7th decade and more than 50% in the 8th. It is critical to find and manage the RAS before it's symptoms appear. The Gold standard for diagnosis of atherosclerotic arterial stenosis is angiography. In this study we will evaluate the prevalence, severity, location and related factors to renal artery stenosis in patients whom referred for coronary angiography in period of July-September in one of the most referral heart center in Iran, "The Tehran heart center" which is doing more than 50 coronary angiography daily.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

All patients reffered to the Tehran Heart center for coronary angiography

Criteria

Inclusion Criteria:

  • age more than 18 years

Exclusion Criteria:

  • contraindication to contrast use
  • not signing consent
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00885768

Locations
Iran, Islamic Republic of
Tehran Heart Center
Tehran, Iran, Islamic Republic of
Sponsors and Collaborators
Imam Khomeini Hospital
Tehran Heart Center
  More Information

No publications provided

Responsible Party: Mohammad Reza Khatami, Kidney Research Center
ClinicalTrials.gov Identifier: NCT00885768     History of Changes
Other Study ID Numbers: RAS001
Study First Received: July 11, 2008
Results First Received: March 9, 2010
Last Updated: May 11, 2011
Health Authority: Iran: Ethics Committee

Keywords provided by Imam Khomeini Hospital:
RAS(renal Artery Stenosis)
Atherosclerosis
angiography

Additional relevant MeSH terms:
Constriction, Pathologic
Renal Artery Obstruction
Pathological Conditions, Anatomical
Kidney Diseases
 Urologic Diseases
Arterial Occlusive Diseases
Vascular Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on May 19, 2013