Trial record 20 of 220 for:    sinusitis

Genetic Factors in Chronic Sinusitis

This study is currently recruiting participants.
Verified December 2012 by University of Chicago
Sponsor:
Information provided by (Responsible Party):
University of Chicago
ClinicalTrials.gov Identifier:
NCT00880516
First received: April 9, 2009
Last updated: September 4, 2013
Last verified: December 2012
  Purpose

The purpose of this study is to learn more about the genetics of chronic sinusitis and identify genes involved in chronic sinusitis.


Condition
Chronic Sinusitis

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Genetic Factors in Chronic Sinusitis

Resource links provided by NLM:


Further study details as provided by University of Chicago:

Primary Outcome Measures:
  • Association of genetic variation with CRS disease status [ Time Frame: Adult age ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

peripheral blood for DNA


Estimated Enrollment: 1200
Study Start Date: April 2009
Estimated Study Completion Date: March 2016
Estimated Primary Completion Date: March 2016 (Final data collection date for primary outcome measure)
Groups/Cohorts
control
Adults with normal sinuses
case
Adults with chronic sinusitis and positive findings on imaging.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Adults with and without chronic sinusitis

Criteria

Inclusion Criteria:

  • Age> 18 years
  • Diagnosis of chronic sinusitis or normal sinuses (with verification by imaging.) You must have a recent CT scan showing either normal sinuses or the presence of sinus disease.

Exclusion Criteria:

  • Genetic or acquired immunodeficiency
  • Ciliary dyskinesia
  • Cystic fibrosis
  • Autoimmune disease
  • Cancer of the sinuses
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00880516

Contacts
Contact: Marcy deTineo, BSN 773-702-5889 mdetineo@surgery.bsd.uchicago.edu

Locations
United States, Illinois
University of Chicago Recruiting
Chicago, Illinois, United States, 60637
Principal Investigator: Jayant Pinto, MD         
Sponsors and Collaborators
University of Chicago
Investigators
Principal Investigator: Jayant Pinto, MD University of Chicago
  More Information

No publications provided

Responsible Party: University of Chicago
ClinicalTrials.gov Identifier: NCT00880516     History of Changes
Other Study ID Numbers: 16749A
Study First Received: April 9, 2009
Last Updated: September 4, 2013
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Sinusitis
Chronic Disease
Paranasal Sinus Diseases
Nose Diseases
Respiratory Tract Diseases
Respiratory Tract Infections
Otorhinolaryngologic Diseases
Disease Attributes
Pathologic Processes

ClinicalTrials.gov processed this record on April 16, 2014