Influence of Tonic and Burst Transcranial Magnetic Stimulation (TMS) Characteristics on Acute Inhibition of Subjective Tinnitus

This study has been completed.
Sponsor:
Information provided by:
University Hospital, Antwerp
ClinicalTrials.gov Identifier:
NCT00878696
First received: April 7, 2009
Last updated: April 8, 2009
Last verified: April 2009
  Purpose

Transcranial magnetic stimulation (TMS) is already broadly used in different areas of neuroscience research. Last year, special attention was drawn to TMS in tinnitus. The aim of the researchers' study is to investigate the stimulation characteristics of TMS in tinnitus patients, in particularly the effect of tonic and burst stimulation of the superior temporal lobe.


Condition Intervention
Tinnitus
Procedure: TMS transcranial magnetic stimulation

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Influence of Tonic and Burst TMS Characteristics on Acute Inhibition of Subjective Tinnitus

Resource links provided by NLM:


Further study details as provided by University Hospital, Antwerp:

Primary Outcome Measures:
  • VAS visual analogue scale [ Time Frame: immediately before and immediately after single session TMS ] [ Designated as safety issue: No ]

Enrollment: 64
Study Start Date: January 2007
Study Completion Date: April 2008
Primary Completion Date: September 2007 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Tinnitus
Tinnitus patients
Procedure: TMS transcranial magnetic stimulation

200 pulses of tonic TMS (see Graph 1) were administered with an intensity at 50% of the maximal TMS device output (50%DO).

The frequency of the tonic pulses was randomly chosen between 1Hz, 5Hz, 10Hz or 20Hz.

Burst stimulation was delivered at a burst frequency of 5, 10 or 20Hz. Each burst consisted of 3, 5 or 10 pulses. The individual pulse rate within a burst was 50 or 100Hz.


  Eligibility

Ages Eligible for Study:   18 Years to 78 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Patients presented to our Multidisciplinary Tinnitus Clinic with tinnitus as a main complaint.

Criteria

Inclusion Criteria:

  • Patients presented to our Multidisciplinary Tinnitus Clinic with tinnitus as a main complaint.

Exclusion Criteria:

  • Patients with known history of epilepsy, pacemakers, cochlear implants, neurostimulators or intracerebral pathology were excluded from the study.
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00878696

Locations
Belgium
Antwerp University Hospital
Edegem, Antwerp, Belgium, 2650
Sponsors and Collaborators
University Hospital, Antwerp
  More Information

No publications provided

Responsible Party: Prof Van de Heyning, UZA
ClinicalTrials.gov Identifier: NCT00878696     History of Changes
Other Study ID Numbers: ITBTMS
Study First Received: April 7, 2009
Last Updated: April 8, 2009
Health Authority: Belgium: Federal Agency for Medicinal Products and Health Products

Additional relevant MeSH terms:
Tinnitus
Hearing Disorders
Ear Diseases
Otorhinolaryngologic Diseases
Sensation Disorders
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms

ClinicalTrials.gov processed this record on October 16, 2014