Energy Expenditure in Weaning From Mechanical Ventilation
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Purpose
During weaning from mechanical ventilation process, the energy expenditure in T tube is greater than pressure support ventilation.
| Condition |
|---|
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Respiration, Artificial Energy Metabolism |
| Study Type: | Observational |
| Study Design: | Time Perspective: Cross-Sectional |
| Official Title: | Energy Expenditure During Weaning From Mechanical Ventilation: Is There Any Difference Between Pressure Support and T-Tube? |
| Enrollment: | 40 |
| Study Start Date: | March 2006 |
| Study Completion Date: | March 2008 |
| Primary Completion Date: | March 2007 (Final data collection date for primary outcome measure) |
The energy expenditure (EE) was measured during the two periods of 30-minutes, with the 10 first minutes being discarded for analysis purposes. The other variables were recorded and monitored during the 10th and the 30th minute, in both pressure support (PS) and t-Tube (TT) modes. Patients were randomized in terms of sequence selection: PS - TT or TT - PS. In the baseline period, patients were receiving mechanical ventilation (Servo 900C and Servo 300; Siemens-Elema, Solna, Sweden), with PS ranging from 10 to 15cmH2O. During the PS mode, patients received assisted pressure ventilation of 10 cmH2O, 5 cmH2O of final positive expiratory pressure, the sensitivity of -1cmH2O and FiO2 of 0.4. During TT mode, oxygen flow was delivered in order to keep the same FiO2 that was provided in PS (0.4) as controlled by monitor screen (Datex Ohmeda S/5 - Compact Airway Module, M-COVX model, Finland). In this mode, an extensor was employed, one end of which was connected to the oxygen-enriched and the other end was secured to a 3-output ("T") connector, which was attached to the patient's ventilatory prosthesis. During the rest period (30 minutes), patients returned to the mechanical ventilation parameters utilized in the baseline period.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Patients with respiratory failure receiving MV fore more than 24 hours, who had been admitted to the Intensive Care Unit (ICU) of the Hospital de Clínicas de Porto Alegre and who met the criteria for weaning from MV according to the parameters previously defined were selected to participate in the study.
Inclusion Criteria:
- Patients with acute respiratory failure receiving MV for over 24 hours, in the ICU of the Hospital de Clínicas de Porto Alegre
Exclusion Criteria:
- Patients with chest drainage, hemodynamic instability (characterized by the use of vasoactive drugs), renal failure, mental status change, agitation, sudoresis, tachycardia, axillary temperature above 38°C and inspiratory oxygen fraction (FiO2) over 0.6.
Contacts and Locations| Brazil | |
| Federal University of Rio Grande do Sul/Hospital de Clínicas de Porto Alegre | |
| Porto Alegre, RS, Brazil | |
| Principal Investigator: | Silvia Vieira, PhD | Federal University of Rio Grande do Sul |
More Information
No publications provided
| Responsible Party: | Silvia Regina Rios Vieira, Hospital de Clínicas de Porto Alegre |
| ClinicalTrials.gov Identifier: | NCT00853060 History of Changes |
| Other Study ID Numbers: | 04-415 |
| Study First Received: | February 25, 2009 |
| Last Updated: | February 26, 2009 |
| Health Authority: | Brazil: National Committee of Ethics in Research |
Keywords provided by Hospital de Clinicas de Porto Alegre:
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energy expenditure mechanical ventilation weaning pressure support ventilation T-tube |
ClinicalTrials.gov processed this record on June 18, 2013