Prognostic Features for Mortality in Young Adults With Pneumonia

This study has been completed.
Sponsor:
Information provided by:
Rambam Health Care Campus
ClinicalTrials.gov Identifier:
NCT00845312
First received: February 15, 2009
Last updated: February 13, 2011
Last verified: February 2009
  Purpose

Pneumonia is a major cause of mortality and morbidity. A large body of evidence concerning the mortality risk factors in elderly patients with pneumonia has been reported; however, less is known about causes of mortality in patients of sixty and less. We noted a relatively substantial rate of short term mortality in this group of patients that were admitted to our institution. Therefore, we aimed to estimate the mortality rate and to identify risk factors for mortality among patients of sixty years old and less that were admitted with community acquired pneumonia.


Condition
Pneumonia

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Prognostic Features for Mortality in Adult Pneumonia Patients at the Age of Sixty and Beneath.

Resource links provided by NLM:


Further study details as provided by Rambam Health Care Campus:

Estimated Enrollment: 1200
Study Start Date: March 2009
Study Completion Date: May 2010
Primary Completion Date: December 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts
Complicated hospitalization

Patients 60 years old or younger, who were diagnosed with community acquired pneumonia (CAP) between March 1, 2005 and December 31, 2008 were retrospectively analyzed for risk factors for severe morbidity or mortality.

was defined as at least one of the following parameters: hospitalization longer than ten days, admission to intensive care unit and in- hospital mortality. Otherwise, the hospitalization was defined uncomplicated .The Rambam hospital Institutional Review Board approved the study.


Detailed Description:

Community acquired pneumonia (CAP) is a major cause of morbidity and mortality. While there is much data about risk factors for severe outcome in the general population, there is less focus on younger group of patients. Therefore, we aimed to detect simple prognostic factors for severe morbidity and mortality in young patients with CAP.

Patients 60 years old or younger, who were diagnosed with CAP (defined as Pneumonia identified 48 hours or less from hospitalization) between March 1, 2005 and December 31, 2008 were retrospectively analyzed for risk factors for severe morbidity or mortality.

Complicated hospitalization was defined as at least one of the following parameters: hospitalization longer than ten days, admission to intensive care unit and in- hospital mortality. Otherwise, the hospitalization was defined uncomplicated

  Eligibility

Ages Eligible for Study:   18 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients that were admitted with community acquired pneumonia to Rambam Medical Center between the dates January 1, 2004 until December 31, 2008

Criteria

Inclusion Criteria:

  • Patients with the diagnosis of community acquired pneumonia Age between 18-60

Exclusion Criteria:

Age less than 18 and more than 60 Transfer from another hospital Hospitalization for any cause other than CAP during the 30 days prior to admission Hospital acquired pneumonia Partial antibiotic treatment before admission.

  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00845312

Locations
Israel
Rambam Medical Center
Haifa, Israel, 31096
Sponsors and Collaborators
Rambam Health Care Campus
Investigators
Study Chair: Zaher S Azzam, MD Head Of Internal Medicine "B"
Principal Investigator: Eyal Braun, MD Deputy Head of Internal Medicine "B"
  More Information

No publications provided by Rambam Health Care Campus

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Eyal Braun M.D., Internal Medicine "B", Rambam Health Care Campus
ClinicalTrials.gov Identifier: NCT00845312     History of Changes
Other Study ID Numbers: CTIL
Study First Received: February 15, 2009
Last Updated: February 13, 2011
Health Authority: Israel: Ministry of Health

Keywords provided by Rambam Health Care Campus:
Age
Mortality

Additional relevant MeSH terms:
Pneumonia
Lung Diseases
Respiratory Tract Diseases
Respiratory Tract Infections

ClinicalTrials.gov processed this record on October 29, 2014