Racial Differences in Orthostatic Tolerance

This study has been completed.
Sponsor:
Information provided by:
Yale University
ClinicalTrials.gov Identifier:
NCT00844181
First received: February 13, 2009
Last updated: NA
Last verified: February 2009
History: No changes posted
  Purpose

Our central hypothesis is that baroreflex sensitivity is attenuated in black women compared to white women, and that this dysregulation will be apparent during orthostatic challenges. We expect that the cumulative stress index (CSI), a measure of maximal orthostatic tolerance, is higher in Black women (BW) compared to White women (WW).


Condition
Orthostatic Tolerance

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Racial Differences in Orthostatic Tolerance

Further study details as provided by Yale University:

Primary Outcome Measures:
  • orthostatic tolerance [ Time Frame: 1 ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

whole blood


Enrollment: 18
Study Start Date: October 2007
Study Completion Date: January 2009
Primary Completion Date: January 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts
0
white women
1
Black women

  Eligibility

Ages Eligible for Study:   18 Years to 25 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Community sample of women of reproductive age

Criteria

Inclusion Criteria:

  • women between 18-25 yrs of age

Exclusion Criteria:

  • history of high blood pressure, uterine fibroids, diabetes, epilepsy
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00844181

Locations
United States, Connecticut
John B. Pierce Laboratory
New Haven, Connecticut, United States, 06519
Sponsors and Collaborators
Yale University
Investigators
Principal Investigator: Nina Stachenfeld, PhD Yale University
  More Information

No publications provided

Responsible Party: Nina Stachenfeld, PhD, John B. Pierce Laboratory
ClinicalTrials.gov Identifier: NCT00844181     History of Changes
Other Study ID Numbers: 0512000875, 3 R01 HL071159-04A1S1
Study First Received: February 13, 2009
Last Updated: February 13, 2009
Health Authority: United States: Institutional Review Board

ClinicalTrials.gov processed this record on July 29, 2014