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Pharmaceutical Care and Clinical Outcomes for the Elderly Taking Potentially Inappropriate Medication

This study is enrolling participants by invitation only.
Sponsor:
Information provided by:
Shin Kong Wu Ho-Su Memorial Hospital
ClinicalTrials.gov Identifier:
NCT00844025
First received: February 12, 2009
Last updated: March 30, 2009
Last verified: March 2009
History of Changes
  Purpose

The investigators propose that clinical pharmacist interventions would reduce the rate of adverse drug events in elderly patients taking potentially inappropriate medication.


Condition Intervention
Elderly
Chronic Disease
 Behavioral: Pharmacist intervention

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Caregiver, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Pharmaceutical Care and Clinical Outcomes for the Elderly Taking Potentially Inappropriate Medication: a Randomized-Controlled Trial

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Shin Kong Wu Ho-Su Memorial Hospital:

Primary Outcome Measures:
  • Number of unsolved drug-related problems [ Time Frame: 14 days after randomization ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Rate of adverse drug event during hospitalization [ Time Frame: 14 days after randomization ] [ Designated as safety issue: No ]
  • Number of potentially inappropriate medication [ Time Frame: 14 days after randomization ] [ Designated as safety issue: No ]

Estimated Enrollment: 120
Study Start Date: February 2009
Estimated Study Completion Date: February 2010
Estimated Primary Completion Date: February 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Pharmacist intervention
Patients in the intervention group will receive pharmaceutical care delivered by clinical pharmacist, which including medication review, medication reconciliation, patient education and recommended actions.
 Behavioral: Pharmacist intervention
Medication review, medication reconciliation, and pharmacotherapy recommendation.
No Intervention: Usual care
Patients randomized to usual care group will receive routine review of medication by ward-based pharmacist and nurse.

  Eligibility

Ages Eligible for Study:   65 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Hospitalized patients aged at least 65 years
  • Taking at least six prescribed medicines regularly, including at least one potential inappropriate medication

Exclusion Criteria:

  • Patients who refused informed consent
  • Discharged before consent could be obtained
  • Cognitive impaired
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00844025

Locations
Taiwan
Shin Kong Wo Ho-Su Memorial Hospital, Department of Pharmacy
Taipei, Taiwan, 111
Sponsors and Collaborators
Shin Kong Wu Ho-Su Memorial Hospital
Investigators
Principal Investigator: Liu Jen Wei, MS Shin Kong Wo Ho-Su Memorial Hospital
  More Information

Publications:

Responsible Party: Tsai Ming Dar/Chief of Shin Kong Wu Ho-Su Memorial Hospital Research and Education Assessment Department, Shin Kong Wu Ho-Su Memorial Hospital
ClinicalTrials.gov Identifier: NCT00844025     History of Changes
Other Study ID Numbers: SKH-8302-98-NDR-05
Study First Received: February 12, 2009
Last Updated: March 30, 2009
Health Authority: Taiwan: Department of Health

Keywords provided by Shin Kong Wu Ho-Su Memorial Hospital:
Adverse drug reaction
Inappropriate medication
Pharmacist
Pharmaceutical care

Additional relevant MeSH terms:
Chronic Disease
Disease Attributes
Pathologic Processes

ClinicalTrials.gov processed this record on May 19, 2013