Intraoperative Blood Pressure and Cognitive Performance

This study is currently recruiting participants. (see Contacts and Locations)
Verified June 2013 by Weill Medical College of Cornell University
Sponsor:
Information provided by (Responsible Party):
Weill Medical College of Cornell University
ClinicalTrials.gov Identifier:
NCT00827385
First received: January 21, 2009
Last updated: June 13, 2013
Last verified: June 2013
  Purpose

The purpose of this study is to prospectively determine the association between incidence of neurological morbidity and minimum fractional blood pressure reached during laminectomy procedures under general anesthesia in hypertensive and normotensive subjects 40 years old and older.


Condition
Cognitive Performance
Hypertension

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Impact of Intraoperative Blood Pressure on Cognitive Performance in Patients With and Without Hypertension: a Prospective Observational Study

Resource links provided by NLM:


Further study details as provided by Weill Medical College of Cornell University:

Primary Outcome Measures:
  • post-operative cognitive performance [ Time Frame: 1 ] [ Designated as safety issue: No ]

Estimated Enrollment: 90
Study Start Date: January 2009
Estimated Primary Completion Date: December 2015 (Final data collection date for primary outcome measure)
Groups/Cohorts
hypertensive
normotensive

  Eligibility

Ages Eligible for Study:   40 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

- individuals 40 years of age and older, undergoing laminectomy under general anesthesia.

Criteria

Inclusion Criteria:

  • English as first language, or as a learned language as long as the patient is proficient
  • No history of any neurological disease with the exception of patients without functional impairment who suffered a single episode of transient ischemic attack
  • No history of axis I psychiatric diagnosis or drug abuse
  • 40 years old or older
  • Undergoing laminectomy under general anesthesia
  • Must not take antihypertensive medication for purposes other than treatment of hypertension

Exclusion Criteria:

  • Anyone who do not fit the inclusion criteria.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00827385

Contacts
Contact: Cynthia Lien, M.D. 212-746-2954 Calien@med.cornell.edu
Contact: Michele Steinkamp, RN 212-746-2953 mls9004@med.cornell.edu

Locations
United States, New York
NewYork-Presbyterian Hospital-Weill Cornell Medical College Recruiting
New York, New York, United States, 10065
Principal Investigator: Cynthia Lien, M.D.         
Sub-Investigator: Kane Pryor, M.D.         
Sub-Investigator: Maria Bustillo, M.D.         
Sub-Investigator: Patricia Fogarty-Mack, M.D.         
Sub-Investigator: David Kopman, M.D.         
Sponsors and Collaborators
Weill Medical College of Cornell University
  More Information

No publications provided

Responsible Party: Weill Medical College of Cornell University
ClinicalTrials.gov Identifier: NCT00827385     History of Changes
Other Study ID Numbers: 0809009986
Study First Received: January 21, 2009
Last Updated: June 13, 2013
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Hypertension
Vascular Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on July 29, 2014