Immune Status of Elderly Population Admitted in an Acute Geriatric Unit
Recruitment status was Recruiting
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Purpose
Ageing is associated with vulnerability against infections leading to increased morbidity with risk of death. Innate and adaptive immunities are altered with ageing responsible of deficits in immune response against pathogens and after vaccination, and favouring the elderly vulnerability against a new pathogen with increased bacterial, viral, and fungal infections.
If immunity has been widely studied in immunosenescence, there are few prospective, comparative studies with elderly ill patients. Moreover among these studies, pathologies are not well defined.
The main objective of our project is to compare the immune state of elderly hospitalised subjects in an acute geriatric unit to the immune state of elderly healthy subjects selected with strict criteria, in order to precise the impact of polypathology and of various pathologies on immunity state.
| Condition | Intervention |
|---|---|
|
Aging |
Other: Blood test and clinical test |
| Study Type: | Interventional |
| Study Design: | Intervention Model: Parallel Assignment Masking: Open Label |
| Official Title: | Immune Status of Elderly Population Admitted in an Acute Geriatric Unit |
- compare the immune state of elderly hospitalised subjects in an acute geriatric unit to the immune state of elderly healthy subjects [ Time Frame: 2 years ] [ Designated as safety issue: No ]
| Estimated Enrollment: | 77 |
| Study Start Date: | January 2009 |
| Estimated Study Completion Date: | July 2011 |
| Estimated Primary Completion Date: | January 2011 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
No Intervention: pathological group
pathological group
|
Other: Blood test and clinical test
Blood test and clinical test
|
|
No Intervention: healthy aged
healthy aged
|
Other: Blood test and clinical test
Blood test and clinical test
|
Eligibility| Ages Eligible for Study: | 75 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Subject of 75 or more years old, female or male
- Subject admitted in the service of short stay gériatrique of the hospital Holy Marguerite, whatever is the motive for admittance
- Subject not being under supervision(guardianship), nor guardianship
- Subject benefiting from a benefit system
- Subject having given its assent of participation or for which the reliable person gave her assent in the case of vulnerable person
Exclusion Criteria:
- Subject of less than 75 years old
- Subject refusing to participate in the study or for whom(which) the reliable person refuses the participation of the subject
Contacts and Locations| Contact: ELODIE CRETEL | elodie.cretel@ap-hm.fr |
| France | |
| HOPITAL DE SAINTE MARGUERITE Service de Gériatrie Sud | Recruiting |
| Marseille, Paca, France | |
| Principal Investigator: ELODIE MD CRETEL | |
| Principal Investigator: | ELODIE CRETEL | Assistance Publique Hopitaux De Marseille |
More Information
No publications provided
| Responsible Party: | Assistance Publique Hopitaux De Marseille |
| ClinicalTrials.gov Identifier: | NCT00823589 History of Changes |
| Other Study ID Numbers: | 2008 -21 |
| Study First Received: | January 14, 2009 |
| Last Updated: | January 26, 2010 |
| Health Authority: | France: Ministry of Health |
Keywords provided by Assistance Publique Hopitaux De Marseille:
|
ELDERLY POPULATION |
ClinicalTrials.gov processed this record on June 18, 2013