Neurophysiology and Anatomy of Severe Intraventricular Hemorrhage (IVH)
Currently, when premature infants develop severe intraventricular hemorrhage (IVH), a type of intracerebral bleed, there are no proven therapeutic interventions to prevent the devastating consequences of this event. These children will be likely to develop cerebral palsy or severe cognitive delays.
The purpose of our study is to characterize differences in brain physiology, imaging, and function between premature infants with severe IVH and controls. The goals for gathering this information are to generate baseline data, which could facilitate early screening for complications of IVH in premature infants. These baseline data would also allow the design and implementation of early therapeutic interventions to help rehabilitate premature infants with severe IVH.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Influence of Altered Cerebral Spinal Fluid and Arterial Flows on Cerebral Processing Functions in Premature Infants With Severe Intraventricular Hemorrhage|
- neurodevelopmental outcome [ Time Frame: 3 years ] [ Designated as safety issue: No ]BSID III scores
|Study Start Date:||January 2009|
|Study Completion Date:||June 2011|
|Primary Completion Date:||June 2011 (Final data collection date for primary outcome measure)|
Infants born at less than 1500g with diagnosis of Grade II or IV IVH
infants born at less than 1500g without IVH on HUS
Please refer to this study by its ClinicalTrials.gov identifier: NCT00817310
|United States, Tennessee|
|Monroe Carell Children's Hospital at Vanderbilt, NICU|
|Nashville, Tennessee, United States, 37232|