Evaluation of the Treatment of Recurrent Corneal Erosions by Anterior Stromal Puncture With Nd: YAG Laser
To evaluate the clinical outcomes in patients with recurrent corneal erosions who received anterior stromal puncture by use of neodymium:yttrium-aluminum-garnet (Nd:YAG) laser.
Recurrent Corneal Erosion
|Study Design:||Observational Model: Cohort
Time Perspective: Retrospective
|Official Title:||Evaluation of the Treatment of Recurrent Corneal Erosions by Anterior Stromal Puncture With Nd: YAG Laser|
- Cure rate of recurrent corneal erosions (frequency of attack and numbers of Nd: YAG laser treatment), intensity of pain relief and visual acuity. [ Time Frame: Before treatment, weekly after the treatment, and monthly after symptom relief ] [ Designated as safety issue: Yes ]
|Study Start Date:||January 2008|
|Study Completion Date:||March 2008|
|Primary Completion Date:||February 2008 (Final data collection date for primary outcome measure)|
Participants: From 2000 to 2005, thirty-three eyes in 33 patients with unilaterally recurrent corneal erosions who showed poor response to conservative managements and were treated with Nd:YAG laser were studied.
Intervention: Anterior corneal stromal puncture with Nd:YAG laser was performed in the loosened epithelium or epithelial defect area. The causes and frequency of corneal erosions and the spot numbers and total energy of the Nd:YAG laser were recorded. Slit-lamp biomicroscopic examination, refraction, corneal topography, and times of laser were reviewed. A questionnaire regarding the preoperative and postoperative difference in the intensity of pain and frequency of corneal erosion was provided.
Main Outcome Measures: Rate of recurrence and pain assessment by numerical rating scale.
|National Taiwan University Hospital|
|Taipei, Taiwan, 100|
|Study Director:||Yu-Chih Ho, MD||Department of Ophthalmology, National Taiwan University Hospital|
|Principal Investigator:||Tzu-Hsun Tsai, MD||Department of Ophthalmology, National Taiwan University Hospital|
|Principal Investigator:||Tzu-Yun Tsai, MD||Department of Ophthalmology, National Taiwan University Hospital|