Evaluation of the Treatment of Recurrent Corneal Erosions by Anterior Stromal Puncture With Nd: YAG Laser
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Purpose
To evaluate the clinical outcomes in patients with recurrent corneal erosions who received anterior stromal puncture by use of neodymium:yttrium-aluminum-garnet (Nd:YAG) laser.
| Condition |
|---|
|
Recurrent Corneal Erosion Trauma |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Retrospective |
| Official Title: | Evaluation of the Treatment of Recurrent Corneal Erosions by Anterior Stromal Puncture With Nd: YAG Laser |
- Cure rate of recurrent corneal erosions (frequency of attack and numbers of Nd: YAG laser treatment), intensity of pain relief and visual acuity. [ Time Frame: Before treatment, weekly after the treatment, and monthly after symptom relief ] [ Designated as safety issue: Yes ]
| Enrollment: | 33 |
| Study Start Date: | January 2008 |
| Study Completion Date: | March 2008 |
| Primary Completion Date: | February 2008 (Final data collection date for primary outcome measure) |
Participants: From 2000 to 2005, thirty-three eyes in 33 patients with unilaterally recurrent corneal erosions who showed poor response to conservative managements and were treated with Nd:YAG laser were studied.
Intervention: Anterior corneal stromal puncture with Nd:YAG laser was performed in the loosened epithelium or epithelial defect area. The causes and frequency of corneal erosions and the spot numbers and total energy of the Nd:YAG laser were recorded. Slit-lamp biomicroscopic examination, refraction, corneal topography, and times of laser were reviewed. A questionnaire regarding the preoperative and postoperative difference in the intensity of pain and frequency of corneal erosion was provided.
Main Outcome Measures: Rate of recurrence and pain assessment by numerical rating scale.
Eligibility| Ages Eligible for Study: | 20 Years to 71 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
to evaluate the clinical outcomes after anterior stromal puncture with Nd:YAG laser in a consecutive series of 33 eyes in 33 patients with unilaterally recurrent corneal erosion.
Inclusion Criteria:
- patients with recurrent corneal erosions who showed poor response to conservative managements and were treated with Nd:YAG laser.
Exclusion Criteria:
- Slit-lamp biomicroscopic examination in both eyes of patient showed any evidence of anterior basement membrane dystrophy.
Contacts and Locations| Taiwan | |
| National Taiwan University Hospital | |
| Taipei, Taiwan, 100 | |
| Study Director: | Yu-Chih Ho, MD | Department of Ophthalmology, National Taiwan University Hospital |
| Principal Investigator: | Tzu-Hsun Tsai, MD | Department of Ophthalmology, National Taiwan University Hospital |
| Principal Investigator: | Tzu-Yun Tsai, MD | Department of Ophthalmology, National Taiwan University Hospital |
More Information
No publications provided
| Responsible Party: | Yu-Chih Hou/Department of Ophthalmology, National Taiwan University Hospital, Organization: Department of Ophthalmology, National Taiwan University Hospital |
| ClinicalTrials.gov Identifier: | NCT00816738 History of Changes |
| Other Study ID Numbers: | 200801035R |
| Study First Received: | August 31, 2008 |
| Last Updated: | January 2, 2009 |
| Health Authority: | Taiwan: Department of Health |
Keywords provided by National Taiwan University Hospital:
|
Nd: YAG laser recurrent corneal erosions trauma anterior stromal puncture |
ClinicalTrials.gov processed this record on May 22, 2013