This study will evaluate the effectiveness of a Web-based program in preventing postpartum depression.

Depression is a mental health condition in which symptoms such as sadness, inability to feel pleasure, and loss of energy interfere with a person's normal life. Postpartum depression is a type of depression experienced by women after giving birth to a child. In this study an intervention for preventing postpartum depression that has been adapted for use over the Internet will be tested. Administering a depression-prevention program over the Internet has several advantages: after the initial investment is made to develop the program, costs are lower for treating each patient; online treatment is more accessible to a greater number of people than any given clinic; and participants who may be worried about a stigma associated with mental health problems often feel more comfortable seeking information through the Internet. Previous research has shown that symptoms of depression can be reduced through Internet-based interventions, but no research has examined such interventions specifically for postpartum depression. The program tested in this study is not aimed at replacing in-person mental health care—in fact, people who have signs of serious depression will be directed to in-person mental health care. Instead, the program is aimed at providing an additional mental health service among the range of available options.

Participants will be allowed to enroll at any time during their pregnancies and will be followed for 6 months after the birth of their children, so the length of participation will vary between 6 and 15 months. After undergoing a screening process, participants will be randomly assigned to receive either the Internet-based course called "Mothers and Babies/Mamás y Bebés" (M&B) or only informational materials. The informational materials will include information about postpartum depression and depression that may occur before childbirth. Participants assigned to the M&B course will receive this same information and will have unlimited access to the M&B interactive mood management intervention online. All participants will undergo monthly assessments for the duration of the study, to be completed online. These assessments will measure mood, depression, and satisfaction with the assigned intervention.

• Depression
• Postpartum Depression

• Behavioral: Mothers and babies Internet course
• Other: Informational materials

• Experimental: Participants will receive information about postpartum depression and access to an interactive mood management course online.
• Other: Participants will receive only information about postpartum depression.

Inclusion Criteria:

• Pregnant
• Fluent in English or Spanish