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Fractional Exhaled Nitric Oxide (FeNO) Result Prediction Factors in Children With Allergic Diseases

This study has been completed.
Sponsor:
Information provided by:
Medical Universtity of Lodz
ClinicalTrials.gov Identifier:
NCT00815984
First received: December 30, 2008
Last updated: February 9, 2010
Last verified: February 2010
  Purpose

In about 800 children with allergic diseases (asthma, allergic rhinitis, atopic dermatitis) the investigators will retrospectively and cross-sectionally analyze the influence/correlation of diagnosis, treatment methods, allergy status (skin prick test results), lung function tests results on/with the concentration of nitric oxide in exhaled breath.


Condition Intervention
Asthma
Allergic Rhinitis
Atopic Dermatitis
Procedure: measurements of lung function tests

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: FeNO Result Prediction Factors in Children With Allergic Diseases

Resource links provided by NLM:


Further study details as provided by Medical Universtity of Lodz:

Primary Outcome Measures:
  • Concentration of nitric oxide in exhaled breath. [ Time Frame: 1-4 months ] [ Designated as safety issue: No ]

Enrollment: 800
Study Start Date: January 2009
Study Completion Date: January 2010
Primary Completion Date: January 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Schoolchildren with asthma.
Schoolchildren with asthma.
Procedure: measurements of lung function tests
Measurement of the concentration of FeNO , measurement of spirometry, plethysmography, exercise challenge test (ECT -spirometric), bronchial obstruction reversibility pharmacological test
Other Names:
  • NO analyzer- Sievers 280i analyzer
  • Spirometry and Plethysmography - Jaeger
  • Exercise provocation test treadmill- Kettler

Detailed Description:

In about 800 children with allergic diseases from our Outpatient Clinic (asthma, allergic rhinitis, atopic dermatitis) we will retrospectively and cross-sectionally analyse the influence/correlation of diagnosis, treatment methods, allergy status (skin prick test results), lung function tests results on/with the concentration of nitric oxide in exhaled breath.

  Eligibility

Ages Eligible for Study:   5 Years to 18 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Children with asthma (allergic), and/or allergic rhinitis and/or atopic dermatitis

Criteria

Inclusion Criteria:

  • Children with asthma (allergic), and/or allergic rhinitis and/or atopic dermatitis

Exclusion Criteria:

  • Other chronic diseases
  • Asthma exacerbation
  • Pregnancy
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00815984

Locations
Poland
Department of Pediatrics and Allergy, N. Copernicus Hospital
Lodz, Poland, 93-513
Sponsors and Collaborators
Medical Universtity of Lodz
Investigators
Study Chair: Iwona Stelmach, MD PhD Prof Department of Pediatrics and Allergy, N. Copernicus Hospital, Lodz, Poland
Principal Investigator: Tomasz Grzelewski, MD, PhD Department of Pediatrics and Allergy, N. Copernicus Hospital, Lodz, Poland
  More Information

No publications provided by Medical Universtity of Lodz

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Iwona Stelmach MD, PhD, Prof, Department of Pediatrics and Allergy, N. Copernicus Hospital, Lodz, Poland
ClinicalTrials.gov Identifier: NCT00815984     History of Changes
Other Study ID Numbers: RNN/135/08/KE
Study First Received: December 30, 2008
Last Updated: February 9, 2010
Health Authority: Poland: Ministry of Health

Keywords provided by Medical Universtity of Lodz:
Asthma
Allergic Rhinitis
Atopic Dermatitis
Children
lung function
skin prick tests
FeNO

Additional relevant MeSH terms:
Dermatitis
Dermatitis, Atopic
Rhinitis
Rhinitis, Allergic, Perennial
Genetic Diseases, Inborn
Hypersensitivity
Hypersensitivity, Immediate
Immune System Diseases
Nose Diseases
Otorhinolaryngologic Diseases
Respiratory Hypersensitivity
Respiratory Tract Diseases
Respiratory Tract Infections
Skin Diseases
Skin Diseases, Eczematous
Skin Diseases, Genetic

ClinicalTrials.gov processed this record on November 20, 2014