Magnetic Resonance Imaging (MRI) in Asymptomatic Patients With Juvenile Idiopathic Arthritis (JIA)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified November 2008 by University Hospital Tuebingen.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
University Hospital Tuebingen
ClinicalTrials.gov Identifier:
NCT00800371
First received: December 1, 2008
Last updated: NA
Last verified: November 2008
History: No changes posted
  Purpose

Juvenile idiopathic arthritis (JIA) may progress asymptomatically leading to joint destruction despite treatment.

The aim of the observational study is to describe patients with silent arthritis comparing symptoms, clinical findings with results of ultrasound and magnetic resonance imaging (MRI).


Condition Intervention
Juvenile Idiopathic Arthritis
Procedure: intra-articular steroid injection

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Diagnostic Value of MRI and Ultrasound in Patients With JIA

Resource links provided by NLM:


Further study details as provided by University Hospital Tuebingen:

Primary Outcome Measures:
  • Definition of patients with silent arthritis. [ Time Frame: every three to six months from recruitment to end of study ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Comparison of diagnostic value of MRI and ultrasound. [ Time Frame: every three to six months from recruitment to end of study ] [ Designated as safety issue: No ]

Estimated Enrollment: 20
Study Start Date: May 2008
Estimated Study Completion Date: June 2010
Estimated Primary Completion Date: December 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
JIA
Patients with JIA
Procedure: intra-articular steroid injection
Steroid injection into otherwise noncontrollable arthritis.

  Eligibility

Ages Eligible for Study:   7 Years to 17 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Patients with JIA

Criteria

Inclusion Criteria:

  • children without symptoms or with only mild joints swelling or with only minimal limited range of motion

Exclusion Criteria:

  • patients with manifest arthritis
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00800371

Contacts
Contact: Nikolay Tzaribachev, MD +49707129 ext 84711 nikolay.tzaribachev@med.uni-tuebingen.de

Locations
Germany
University Children's Hospital Recruiting
Tuebingen, Baden-Wuerttemberg, Germany, 72076
Principal Investigator: Nikolay Tzaribachev, MD         
Sponsors and Collaborators
University Hospital Tuebingen
Investigators
Principal Investigator: Nikolay Tzaribachev, MD University Hospital Tuebingen
  More Information

No publications provided

Responsible Party: Nikolay Tzaribachev, MD, University Children's Hospital
ClinicalTrials.gov Identifier: NCT00800371     History of Changes
Other Study ID Numbers: Silent Arthritis PROSPECT 2008
Study First Received: December 1, 2008
Last Updated: December 1, 2008
Health Authority: Germany: Federal Institute for Drugs and Medical Devices

Keywords provided by University Hospital Tuebingen:
JIA

Additional relevant MeSH terms:
Arthritis
Arthritis, Juvenile Rheumatoid
Joint Diseases
Musculoskeletal Diseases
Arthritis, Rheumatoid
Rheumatic Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases

ClinicalTrials.gov processed this record on July 26, 2014