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Reproducibility of Magnetic Resonance Myocardial Salvage Index

This study has been completed.
Sponsor:
Information provided by:
University of Leipzig
ClinicalTrials.gov Identifier:
NCT00794300
First received: November 19, 2008
Last updated: NA
Last verified: November 2008
History: No changes posted
  Purpose

The myocardial salvage assessed by using multimodal cardiac magnetic resonance imaging is a rather new technique which can be used as a surrogate endpoint to reduce the sample size in studies comparing different reperfusion strategies in myocardial infarction. As reproducibility of myocardial salvage has not been evaluated appropriately, we aim to scan 20 patients on 2 subsequent days to evaluate reproducibility of myocardial salvage index.


Condition Intervention
Myocardial Infarction
 Device: second magnetic resonance imaging scan

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Reproducibility of Myocardial Salvage Index in Acute Myocardial Infarction by Cardiac Magnetic Resonance Imaging

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University of Leipzig:

Primary Outcome Measures:
  • Myocardial salvage index reproducibility [ Time Frame: 2 days ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • infarct size reproducibility [ Time Frame: 2 days ] [ Designated as safety issue: No ]
  • area at risk reproducibility [ Time Frame: 2 days ] [ Designated as safety issue: No ]
  • microvascular obstruction reproducibility [ Time Frame: 2 days ] [ Designated as safety issue: No ]

Groups/Cohorts Assigned Interventions
Acute myocardial infarction patients Device: second magnetic resonance imaging scan

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

ST-elevation myocardial infarction

Criteria

Inclusion Criteria:

  • ST-elevation myocardial infarction
  • Primary percutaneous coronary intervention

Exclusion Criteria:

  • Contraindications for magnetic resonance imaging
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00794300

Locations
Germany
University of Leipzig - Heart Center
Leipzig, Germany, 04289
Sponsors and Collaborators
University of Leipzig
Investigators
Principal Investigator: Holger Thiele, MD University of Leipzig
  More Information

No publications provided by University of Leipzig

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

ClinicalTrials.gov Identifier: NCT00794300     History of Changes
Other Study ID Numbers: Repro100
Study First Received: November 19, 2008
Last Updated: November 19, 2008
Health Authority: Germany: Ethics Commission

Keywords provided by University of Leipzig:
reproducibility
contrast agent
magnetic resonance imaging
 infarct size
myocardial salvage index
myocardial salvage assessment

Additional relevant MeSH terms:
Infarction
Myocardial Infarction
Ischemia
Pathologic Processes
Necrosis
 Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases

ClinicalTrials.gov processed this record on May 23, 2013