Effect of Cognitive Behavioral Therapy in OCD Highlighted by Neuropsychological Tests and MRI: Pathophysiology and Treatment Outcome Predictors

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Aarhus
ClinicalTrials.gov Identifier:
NCT00792038
First received: November 14, 2008
Last updated: August 1, 2012
Last verified: August 2012
  Purpose

OCD patients are assessed before and after treatment using diagnostic tools, rating scales neuropsychological assessment and functional and structural MR-scans.


Condition
Obsessive-Compulsive Disorder

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Effect of Cognitive Behavioral Therapy in OCD Highlighted by Neuropsychological Tests and MRI: Pathophysiology and Treatment Outcome Predictors

Resource links provided by NLM:


Further study details as provided by University of Aarhus:

Primary Outcome Measures:
  • Y-Bocs [ Time Frame: Before and after treatment approx 20 weeks apart ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Full blood


Enrollment: 88
Study Start Date: January 2009
Study Completion Date: July 2012
Primary Completion Date: July 2012 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
OCD patients
2
Normal Controls

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

OCD patients from the primary care clinics in middle Jutland, Denmark

Criteria

Inclusion Criteria:

1. Steady state medication 3 months prior to the study

Exclusion Criteria:

  1. History of head trauma or other organic brain disease
  2. Pregnancy.
  3. Pacemaker or other ferromagnetic materials in the body.
  4. Comorbid psychiatric illnesses assessed using SCAN- interview (30) other than moderate depression (Ham-D<17) or anxiety disorders.
  5. Antipsychotics
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00792038

Locations
Denmark
Aarhus University Hospital, Risskov
Risskov, Denmark, 8240
Sponsors and Collaborators
University of Aarhus
Investigators
Principal Investigator: Tue BH Hartmann Aarhus University Hospital, Risskov
Study Director: Sanne Kjær Aarhus University Hospital, Risskov
  More Information

No publications provided by University of Aarhus

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: University of Aarhus
ClinicalTrials.gov Identifier: NCT00792038     History of Changes
Other Study ID Numbers: M-20080161
Study First Received: November 14, 2008
Last Updated: August 1, 2012
Health Authority: Denmark: Danish Dataprotection Agency

Keywords provided by University of Aarhus:
Psychological tests
Magnetic Resonance Imaging
Cognitive therapy

Additional relevant MeSH terms:
Compulsive Personality Disorder
Obsessive-Compulsive Disorder
Personality Disorders
Mental Disorders
Anxiety Disorders

ClinicalTrials.gov processed this record on September 18, 2014