The Efficacy of Nurse-Driven, Protocol Guided Ventilator Weaning in a Medical-Surgical Intensive Care Unit (ICU)
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Purpose
- Mechanically ventilated patients weaned by nurse-driven ventilator weaning protocol will have a mean length of stay on ventilator at least one day shorter than patients weaned by physician-initiated, non-protocol methods
- Mechanically ventilated patients weaned by nurse-driven ventilator weaning protocol will have al least similar Ventilator, ICU, and Hospital Length Of Stay (LOS) compared to patients weaned by physician-initiated, non-protocol method
- Nurse-driven ventilator weaning protocol is well accepted by other services: physicians, nurses, and respiratory therapists.
| Condition |
|---|
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Vent Weaning in Medical- Surgical ICUs |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Prospective |
| Official Title: | The Efficacy of Nurse-Driven, Protocol Guided Ventilator Weaning in a Medical-Surgical ICU |
- Average Length of Stay on Ventilator [ Designated as safety issue: Yes ]
- ICU mortality [ Designated as safety issue: No ]
- Hospital mortality [ Designated as safety issue: No ]
- Treatment intensity and resource allocation: Cost of ICU care per year [ Designated as safety issue: No ]
- Level of acceptance of nurse-driven vent weaning protocol [ Designated as safety issue: No ]
| Enrollment: | 215 |
| Study Start Date: | December 2007 |
| Study Completion Date: | June 2008 |
| Primary Completion Date: | June 2008 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
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1
Mechanically ventilated patients weaned by nurse-driven ventilator weaning protocol
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Detailed Description:
Ventilatory support is one of the most common indications for admission to ICU (1).
The duration of mechanical ventilation is associated with several serious complications, increase mortality, prolong ICU stay, and increase hospital cost (7,8).
Traditionally, the process of ventilator weaning is initiated and carried out my physicians.
Recently, there have been few studies that supported the utility of protocol guided weaning algorithms. Its use have been associated with earlier initiation of weaning, leading to shorter ventilator time, and a trend for shorter ICU length-of-stay and lower hospital costs (1,2,4,9) Several studies have also shown the relative safety of utilizing nursing (3) and RT staff alone or in cooperation with medical staff in the weaning of patients from mechanical ventilation (1,2,6).
We recently developed a nurse-driven ventilator weaning protocol for all ICUs at St. Luke's and Roosevelt hospitals. The protocol was approved by the Critical Care Committee and is implemented as of May 2007. All ICU nurses, respiratory therapists, and ICU physicians have been educated on this protocol We plan to prospectively collect data to look at length of stay on mechanical ventilation in patients weaned by nurse-driven ventilator weaning protocol. We plan to compare such data to retrospectively collected ventilator LOS data in patients weaned by physician-initiated ventilator weaning method.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Probability Sample |
Mechanically Ventilated Patients in Medical-Surgical ICU
Inclusion Criteria:
- Receiving MV for at least 24 hours in the ICU
- Meeting established protocol criteria for a vent wean trial
Exclusion Criteria:
- Patients in whom MV was actively withdrawn for terminal wean
- Brain dead patients on MV
- Age <18 years old
- Transfers from other hospitals or health care facility who were ventilator dependent
Contacts and Locations
More Information
Publications:
| Responsible Party: | Hassan Khouli, MD, St. Luke's Roosevelt Hospital |
| ClinicalTrials.gov Identifier: | NCT00786617 History of Changes |
| Other Study ID Numbers: | 07-122 |
| Study First Received: | November 5, 2008 |
| Last Updated: | November 5, 2008 |
| Health Authority: | United States: Institutional Review Board |
ClinicalTrials.gov processed this record on May 19, 2013