A Survey to Evaluate the Rate of Abnormal Glucose Tolerance Among Hong Kong Chinese Subjects With Coronary Heart Disease
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Purpose
Hypothesis: there is a high prevalence rate of diabetes, including asymptomatic undiagnosed glucose intolerance, among subjects with coronary heart disease in Hong Kong.
A cross-sectional survey is planned to study the rate of undiagnosed diabetes and glucose intolerance among the Chinese patients with coronary heart disease in Hong Kong. The survey results will be important for us to plan the logistics to investigate and manage the potential glucose abnormality of our heart disease patient.
| Condition |
|---|
|
Coronary Heart Disease Diabetes Mellitus |
| Study Type: | Observational |
| Study Design: | Observational Model: Case-Only Time Perspective: Retrospective |
| Official Title: | A Cross-sectional Observational Survey to Evaluate the Rate of Diabetes and Glucose Intolerance (Both Diagnosed and Undiagnosed) Among Hong Kong Chinese Subjects With Coronary Heart Disease |
| Estimated Enrollment: | 3000 |
| Study Start Date: | October 2008 |
| Estimated Study Completion Date: | January 2014 |
| Estimated Primary Completion Date: | September 2013 (Final data collection date for primary outcome measure) |
Diabetes is becoming an epidemic in Hong Kong, affecting over 10% of population and causing a major burden to the health care system. Over 30-40% of patients admitted to the medical wards of the Hospital Authority hospitals have diabetes as a contributory factor. It was estimated that thirty to fifty percent of patients with stroke, heart failure or acute myocardial infarction have diabetes as a key causative factor. However, the exact prevalence rate of diabetes, including asymptomatic undiagnosed glucose intolerance, among subjects with coronary heart disease is still unknown in Hong Kong. Many heart disease patients with undiagnosed diabetes remained being untreated on their abnormal glycemic status, which will further aggravate the heart disease and impair the prognosis.
The investigators plan to conduct a cross-sectional survey to study the rate of undiagnosed diabetes and glucose intolerance among the Chinese patients with coronary heart disease in Hong Kong. The survey results will be important for us to plan the logistics to investigate and manage the potential glucose abnormality of our heart disease patient.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Hong Kong Chinese with history of coronary heart disease being diagnosed in 2008 in HA hospitals
Inclusion Criteria:
- Patients aged 18 years
- Subjects admitted to Hospital Authority hospital as in-patients (AHNH) with the diagnosis of coronary heart disease (ICD code 410-414) during the period 1 April 2007 to 31 March 2008.
- Subjects admitted to AHNH for the procedure Percutaneous Coronary Intervention (PCI) to manage coronary heart disease.
Exclusion Criteria:
- Known Type 1 diabetes defined as history of ketosis [acute symptoms with heavy ketonuria (>3+) or ketoacidosis] or heavy ketonuria (3+) or continuous requirement of insulin treatment within one year of diagnosis and thereafter.
- Patients with terminal malignancy or other life-threatening diseases with less than 6-month expected survival
- Patients with a mental condition rendering the subject unable to understand the nature, scope, and possible consequences of the study
Contacts and Locations More Information
No publications provided
| Responsible Party: | Gary Ko, Hong Kong Institute of Diabetes and Obesity |
| ClinicalTrials.gov Identifier: | NCT00786175 History of Changes |
| Other Study ID Numbers: | CRE-2008.336 |
| Study First Received: | November 5, 2008 |
| Last Updated: | October 15, 2010 |
| Health Authority: | Hong Kong: Ethics Committee |
Additional relevant MeSH terms:
|
Coronary Artery Disease Myocardial Ischemia Coronary Disease Diabetes Mellitus Heart Diseases Cardiovascular Diseases |
Arteriosclerosis Arterial Occlusive Diseases Vascular Diseases Glucose Metabolism Disorders Metabolic Diseases Endocrine System Diseases |
ClinicalTrials.gov processed this record on May 23, 2013