Effects of a Peripheral Nerve Block on Biomarkers of Pain and Inflammation
The purpose of this study is to determine the effect of a local anesthetic nerve block on markers of inflammation and pain after a sunburn. This is important because it may provide information regarding the way that nerve blocks help with the treatment of pain and in particular provide preemptive analgesia.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Primary Purpose: Prevention
|Official Title:||Effect of Peripheral Nerve Block on Inflammatory and Nociceptive Biomarkers in a UV-B Burn Model in Humans|
- Measurement of the effect of a preemptive peripheral nerve block on the hyperalgesic response to an artificially induced sunburn.
- Measurement of the effect of a preemptive peripheral nerve block on the release of pro-inflammatory cytokines.
|Study Start Date:||October 2007|
|Estimated Study Completion Date:||July 2008|
|United States, California|
|Stanford University School of Medicine|
|Stanford, California, United States, 94305|
|Principal Investigator:||Martin S Angst||Stanford University|