AKIN Criteria: Acute Kidney Injury After On-Pump Coronary Artery Bypass Graft (CABG)
The purpose of this study is evaluate clinical outcomes and 30-day mortality after on-pump CABG.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||AKIN (Acute Kidney Injury Network): Acute Kidney Injury After On-Pump Coronary Artery Bypass Graft Surgery|
- To test the hypothesis that patients with acute kidney injury after on-pump CABG have higher 30-day mortality [ Time Frame: 30 days ] [ Designated as safety issue: No ]
- To compare clinical outcomes in patients with and without acute kidney injury after on-pump CABG [ Time Frame: 30 days ] [ Designated as safety issue: No ]
|Study Start Date:||January 2003|
|Study Completion Date:||January 2008|
|Primary Completion Date:||January 2008 (Final data collection date for primary outcome measure)|
Patients without acute kidney injury after on-pump CABG
Patients with acute kidney injury after on-pump CABG
Eight hundred and seventeen patients was enrolled in this series and divided into to groups: Group AKI (-) - patients without acute kidney injury after on-pump CABG. Group AKI (+) - patients with acute kidney injury after on-pump CABG. AKI was defined as an absolute increase in serum creatinine (SCr) of more than or equal to 0.3 mg/dl (≥ 26.4 μmol/l) or a percentage increase in SCr of more than or equal to 50% (1.5-fold from baseline). The change in SCr concentration was defined as the difference between immediate postoperative concentration and the highest concentration during the stay in ICU. Clinical Outcomes and 30-day mortality was evaluate in this patients.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00780845
|Study Director:||Lilia N Maia, PhD||São José do Rio Preto Medical School|