Chronic Knee Pain Study (JRPIT)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2011 by University of Pittsburgh.
Recruitment status was  Active, not recruiting
Sponsor:
Collaborator:
Information provided by:
University of Pittsburgh
ClinicalTrials.gov Identifier:
NCT00776932
First received: October 21, 2008
Last updated: August 12, 2011
Last verified: August 2011
  Purpose

Specific Aims: 1) To examine differences between AA and white patients with knee OA in willingness to consider knee joint replacement. 2) To examine the relationship between socio-cultural factors and patient willingness to consider joint replacement. 3) To examine how demographic, socio-cultural, and clinical factors mediate the relationship between race and patient willingness. 4) To examine the relationship between patient willingness and referral to orthopedic care for knee OA (secondary aim).

Experimental design/Methodology: A cross-sectional survey study design will be used to examine socio-cultural and clinical factors that may vary by race/ethnicity and may be determinants of willingness to consider joint replacement as a treatment option. Patients with symptomatic and radiographic knee OA from the primary care clinics will be surveyed. Only individuals with knee OA of sufficient severity that would be considered candidates for joint replacement will be included. Analytic strategies include ordinal logistic regression, path analysis, and regression trees.

Subject population: The study sample will consist of approximately 133 African American and 419 white patients with OA of the knee in a primary care setting.


Condition
Knee Osteoarthritis

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Disparity in Joint Replacement: Pathway to Intervention

Further study details as provided by University of Pittsburgh:

Primary Outcome Measures:
  • Compared to whites, AAs with knee OA will be less willing to consider joint replacement. Logistic regression will be used to model the categorical measure of willingness, if preliminary analyses indicate dichotomizing this measure. [ Time Frame: Study Completion ] [ Designated as safety issue: No ]

Estimated Enrollment: 522
Study Start Date: June 2007
Estimated Study Completion Date: June 2013
Primary Completion Date: August 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts
Knee OA
Those over the age of 50 who have frequent pain in their knee that has lasted for at least six months.

  Eligibility

Ages Eligible for Study:   50 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

African Americans and Whites over the age of 50 with chronic knee pain.

Criteria

Inclusion Criteria:

  • over age 50
  • chronic knee pain
  • radiographic evidence of knee OA

Exclusion Criteria:

  • previous joint replacement
  • inflammatory arthritis
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00776932

Locations
United States, Pennsylvania
University of Pittsburh Arthritis Research Center
Pittsburgh, Pennsylvania, United States, 15213
Sponsors and Collaborators
University of Pittsburgh
Investigators
Principal Investigator: C. Kent Kwoh, MD University of Pittsburgh
  More Information

No publications provided

Responsible Party: Said Ibrahim, University of Pittsburgh
ClinicalTrials.gov Identifier: NCT00776932     History of Changes
Other Study ID Numbers: 07040263, 1 P60 AR05473-01
Study First Received: October 21, 2008
Last Updated: August 12, 2011
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Osteoarthritis
Osteoarthritis, Knee
Arthritis
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases

ClinicalTrials.gov processed this record on October 22, 2014