Influence of Rapydan on Clinical Chemistry and Hematology Measurements
There is an increasing awareness of the importance of treating procedure-related pain. Patients undergoing vascular access procedures are often afraid of needles and the discomfort associated with injections. This type of pain and/or fear can be stressful to patients.  For prevention of the pain associated with these procedures, the hospital is using Rapydan plasters. Rapydan consists out of two local anesthetics: lidocaine and tetracaïne. Rapydan produces topical anesthesia after an application time of 30 minutes and is used in the Martini Hospital for pain relieve by venipuncture and IV cannulation. The venous blood draining the anaesthetized skin contains a higher blood concentration of the local anesthetics than does venous blood in other parts of the body  Although the concentrations of the local anesthetics are low in patients with normal skin, the question is whether the presence of the local anesthetics which Rapydan contains might influence routine measurements in clinical chemistry and hematology.
|Study Design:||Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
|Official Title:||Does Rapydan Influence Routine Clinical Chemistry and Hematology Measurements?|
- Routine Clinical Chemistry measurements differences [ Time Frame: 1 ] [ Designated as safety issue: No ]
|Study Start Date:||November 2009|
|Study Completion Date:||May 2010|
|Primary Completion Date:||May 2010 (Final data collection date for primary outcome measure)|
Internal control. Blood from both arms will be drawn. Only one arm of the subject is treated with Rapydan.
lidocaine / tetracaine 70/70 mg patch
Other Name: Lidocaine Tetracaine Patch
Please refer to this study by its ClinicalTrials.gov identifier: NCT00765934
|Study Director:||Rob Oude Elferink, MSc||LabNoord|