Skin Imaging With Technologies in Development

This study is enrolling participants by invitation only.
Sponsor:
Collaborator:
Beckman Laser Institute University of California Irvine
Information provided by (Responsible Party):
Montana Compton, University of California, Irvine
ClinicalTrials.gov Identifier:
NCT00764920
First received: September 30, 2008
Last updated: July 31, 2014
Last verified: July 2014
  Purpose

The purpose of this research study is to develop new methods of looking at the human skin. Each device has its own method of taking images of the skin. The data from these devices will be compared and analyzed.


Condition Intervention
Pigmented Skin Lesion of Uncertain Nature
Device: diagnostic imaging

Study Type: Observational
Official Title: Non-invasive Imaging Modalities for Assessment of Normal and Lesional Skin

Resource links provided by NLM:


Further study details as provided by University of California, Irvine:

Primary Outcome Measures:
  • Learn information about the human skin which could be useful for diagnosis or guiding treatment. [ Time Frame: 4 weeks ] [ Designated as safety issue: Yes ]

Estimated Enrollment: 350
Study Start Date: October 2008
Estimated Study Completion Date: October 2018
Estimated Primary Completion Date: October 2018 (Final data collection date for primary outcome measure)
Intervention Details:
    Device: diagnostic imaging
    imaging
Detailed Description:

The devices being studied are:

  1. Laser Speckle Imaging (LSI): LSI provides information about relative blood flow in a tissue. In skin it can be used to determine what areas have more blood flow and whether a particular intervention or treatment affects blood flow.
  2. Optical Coherence Tomography (OCT) and Optical Doppler Tomography (ODT): OCT and ODT can provide pictures of blood vessels in an area of the body and can also tell how fast blood is flowing in that area.
  3. Photon Migration Spectroscopy (PMS): PMS can provide information about the amount of blood, oxygen, fat and water is in a tissue.
  4. Multi-Spectral Imaging (MI): MI allows operators to get a 3 dimensional image of structures within the skin.
  5. Multiphoton Microscopy (MPM) MPM also allows imaging of structures within the skin.
  6. Surface Enhanced Resonance Raman Spectroscopy (SERRS): SERRS can be used to determine the chemical components of structures within tissue.
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

community sample

Criteria

Inclusion Criteria:

  • adult male or female 18 years of age or older

Exclusion Criteria:

  • Younger than 18 years old
  • pregnant woman
  • breast feeding
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00764920

Locations
United States, California
Beckman Laser Institute Medical clinic
Irvine, California, United States, 92612
Sponsors and Collaborators
Montana Compton
Beckman Laser Institute University of California Irvine
Investigators
Principal Investigator: Kristen M Kelly, MD Beckman Laser Institute University of California Irvine
  More Information

No publications provided

Responsible Party: Montana Compton, Administrative Nurse Research Coordinator Beckman Laser Institute, University of California, Irvine
ClinicalTrials.gov Identifier: NCT00764920     History of Changes
Other Study ID Numbers: LAMMP-DOS-WIFI-MET-SMM
Study First Received: September 30, 2008
Last Updated: July 31, 2014
Health Authority: United States: Institutional Review Board

Keywords provided by University of California, Irvine:
human skin

Additional relevant MeSH terms:
Pigmentation Disorders
Skin Diseases

ClinicalTrials.gov processed this record on October 29, 2014