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The Body's Response to Aerobic Versus Resistance Exercise

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Wayne Campbell, Purdue University
ClinicalTrials.gov Identifier:
NCT00761163
First received: September 25, 2008
Last updated: January 16, 2013
Last verified: January 2013
  Purpose

The purpose of this study is to identify the body's response to aerobic vs. resistance exercise. Throughout this study, we will examine food intake, appetite, and physical and mental well-being before, during, and after aerobic and resistance exercise.


Condition Intervention
Exercise
Other: Resistance Exercise
Other: Aerobic Exercise
Other: Control (Non-exercise)

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention

Resource links provided by NLM:


Further study details as provided by Purdue University:

Primary Outcome Measures:
  • Physical well being via electrocardiogram and body composition [ Time Frame: 5-6 weeks ] [ Designated as safety issue: No ]
  • Mental well being via questionnaires [ Time Frame: 5-6 weeks ] [ Designated as safety issue: No ]

Enrollment: 25
Study Start Date: February 2007
Study Completion Date: November 2008
Primary Completion Date: November 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1 Other: Resistance Exercise
The subjects will complete 2 resistive exercise sessions on non-consecutive days that will be supervised by our laboratory staff. The following exercises will be performed using the Keiser Sports Health equipment in Ismail Health, Exercise, and Nutrition Center: seated row, double leg press, seated leg curl, chest press, and leg extension. The subjects will individually perform 3 sets of 8-10 repetitions at an exercise intensity of 70% of pre-determined maximal strength for these exercises. Each repetition will be performed in a slow (six to eight seconds) uniform fashion, giving equal time to the concentric (muscle shortening) and eccentric (muscle lengthening) portions. One minute of rest will be allowed between sets. The last repetition of the third set of each exercise will be done to voluntary fatigue or the performance of 12 repetitions.
Experimental: 2 Other: Aerobic Exercise
The subjects will complete 2 aerobic exercise sessions on non-consecutive days that will also be supervised by our laboratory staff. The subjects will perform 45 minutes of aerobic exercise on a stationary bike at an exercise intensity of 70% of their heart-rate reserve.
Experimental: 3 Other: Control (Non-exercise)
The subjects will also complete 2 non-exercise sessions on non-consecutive days that will also be supervised by our laboratory staff. These sessions will consist of incorporating diversionary tasks throughout a 45 minute period consisting of a variety of motor and psychological tasks (tests of hand steadiness, alertness, optical illusions, mental acuity, etc.)

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Body mass index between 18-29 kg/m2
  • Weight stable (< 4.5 kg weight change within last 6 months)
  • Non-smoking
  • Constant habitual activity patterns within last 3 months
  • Non-diabetic
  • Resistive exercise training (≥ 2 times a week) based on reported physical activity levels (questionnaire)
  • Aerobic exercise training (≥ 2 times a week, 30-min sessions) based on reported physical activity levels (questionnaire)
  • Confirmation of acceptability of eating the study test foods (macaroni casserole)
  • Approved to participate in this study by our study physician and principle investigator

The older subjects must also meet the following eligibility criteria:

  • Age range: 65 years and older
  • Body fat (women: <38%; men: <28%)
  • Normal resting EKG as assessed by a Cardiologist

The younger subjects must also meet the following eligibility criteria:

  • Age range: 18-29 years
  • Body fat (women: <28%; men: <18%)

Exclusion Criteria:

  • Body mass index: outside of the 18-29 kg/m2 range
  • Gained or lost > 4.5 kg within the last 6 months
  • Smoker (currently or within the last year)
  • Intermittently been involved in a diet and/or exercise program within the last 3 months
  • Clinically diagnosed as diabetic
  • Did not perform resistive exercise training (currently or within the last 3 months) based on reported physical activity levels (questionnaire)
  • Did not perform adequate aerobic exercise (currently or within the last 3 months) based on physical activity levels (questionnaire)
  • Study food is found to be unacceptable for consumption by the subject
  • Unapproved to participate in this study by our study physician and principle investigator

The older subjects:

  • Age range: <65 yrs
  • Body fat (women: >38%; men: >28%)
  • Abnormal resting EKG (interpreted by a cardiologist) and assessed (for study exclusion) by our study physician, Arthur Rosen, MD

The younger subjects:

  • Age range: outside the >29 yrs or <18 yrs
  • Body fat (women: >28%; men: >18%)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00761163

Locations
United States, Indiana
Purdue University
West Lafayette, Indiana, United States, 47907
Sponsors and Collaborators
Purdue University
  More Information

No publications provided by Purdue University

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Wayne Campbell, Wayne Campbell, Ph. D., Purdue University
ClinicalTrials.gov Identifier: NCT00761163     History of Changes
Other Study ID Numbers: 0701004892, NIH/NIA 5R01AG021911
Study First Received: September 25, 2008
Last Updated: January 16, 2013
Health Authority: United States: Institutional Review Board

Keywords provided by Purdue University:
The purpose of this study is to identify the body's response to aerobic vs. resistance exercise

ClinicalTrials.gov processed this record on November 25, 2014