Cognitive and Functional Status and Dialysis Outcomes in Older Hemodialysis Patients
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Purpose
The purpose of this study is to estimate how quickly cognitive status and functional status in older patients on hemodialysis declines.
| Condition |
|---|
|
Dementia Cognition End-Stage Renal Disease |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Prospective |
| Official Title: | Cognitive and Functional Status and Dialysis Outcomes in Older Hemodialysis Patients |
| Estimated Enrollment: | 150 |
| Study Start Date: | November 2007 |
| Estimated Study Completion Date: | November 2014 |
| Estimated Primary Completion Date: | November 2013 (Final data collection date for primary outcome measure) |
Dialysis outcome measures, which predict morbidity and mortality of younger patients on renal replacement therapy, such as dialysis clearance, do not correlate with survival of the elderly patients on hemodialysis. Survival of older patients on hemodialysis is significantly worse when compared to that of the younger patients. Conditions commonly affecting older adults, such as functional decline, cognitive impairment, depression and declining quality of life have not been well studied in hemodialysis population. There may be an important relationship between these measurements and outcomes in older dialysis patients. Institution of appropriate age-specific interventions could result in improved health status and mortality of older patients on hemodialysis. Our broad objective is to better understand global functioning of the elderly dialysis patients and its possible impact on dialysis outcomes in attempt to improve health care of the older patients receiving hemodialysis.
Eligibility| Ages Eligible for Study: | 60 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
All prevalent and incident hemodialysis patients over the age of 60, receiving hemodialysis treatments at the University of Chicago outpatient dialysis program at the time of the study will be invited to participate.
Inclusion Criteria:
- Prevalent and incident hemodialysis patients over the age of 60, receiving hemodialysis treatments at the University of Chicago outpatient dialysis program.
Exclusion Criteria:
- Patients 59 and younger, and patients with the following medical conditions: malignancies currently requiring chemotherapy or radiation therapy, severe heart failure (NYHA class IV), known HIV infection, or currently active hepatic encephalopathy.
Contacts and Locations| Contact: Tiffany Perry, MA | 7738345830 | tperry@medicine.bsd.uchicago.edu |
| United States, Illinois | |
| University of Chicago Chronic Hemodialysis Centers | Recruiting |
| Chicago, Illinois, United States, 60617 | |
| Contact: Tiffany Perry, MA 773-834-5830 tperry@medicine.bsd.uchicago.edu | |
| Principal Investigator: Nicole Stankus, MD, MSc | |
| Sub-Investigator: Jennifer Ennis, MD | |
| Principal Investigator: | Nicole Stankus, MD, MSc | University of Chicago |
More Information
No publications provided
| Responsible Party: | Nicole Stankus MD, MSc, Assistant Professor of Medicine, The University of Chicago |
| ClinicalTrials.gov Identifier: | NCT00739843 History of Changes |
| Other Study ID Numbers: | 15813B |
| Study First Received: | August 20, 2008 |
| Last Updated: | August 21, 2008 |
| Health Authority: | United States: Institutional Review Board |
Keywords provided by University of Chicago:
|
Dementia, Cognitive Disorders, Hemodialysis |
Additional relevant MeSH terms:
|
Dementia Kidney Diseases Kidney Failure, Chronic Brain Diseases Central Nervous System Diseases Nervous System Diseases |
Delirium, Dementia, Amnestic, Cognitive Disorders Mental Disorders Urologic Diseases Renal Insufficiency, Chronic Renal Insufficiency |
ClinicalTrials.gov processed this record on June 17, 2013