Acute Pain Episodes in Patients Under Opioid Maintenance Therapy : Clinical Management and Long Term Effects
To define a rational pharmacological management of pain for the subjects under opioid maintenance therapy (methadone or buprenorphine), it is first of all necessary to estimate the efficiency of the current practices on pain management as well as their potentially noxious consequences, in particular on the long term opioid maintenance therapy.
The objective of the study is to compare the efficiency of the opioid maintenance therapy according to the arisen of an acute painful phenomenon requiring an analgesic management for these patients. At first, this work will allow to determine the results on acute pain of the current practices for these patients. The comparison of the long term consequences on opioid maintenance therapy between the patients that presented an acute painful phenomenon and the control patients should help to improve acute pain management for these patients while limiting the risk of relapse in the abused consumption of psychoactive substances.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Acute Pain Episodes in Patients Under Opioid Maintenance Therapy : Clinical Management and Long Term Effects|
- Retention rate under buprenorphine or methadone treatment defined as the percentage of patients still under treatment during the follow-up [ Time Frame: 1, 3, 6 and 12 months ] [ Designated as safety issue: No ]
- pain, anxiety, drugs, alcohol and other substances abuse and dependence, drug prescription (included for pain treatment and opioid maintenance) [ Time Frame: 1, 3, 6 and 12 months ] [ Designated as safety issue: Yes ]
|Study Start Date:||April 2008|
|Study Completion Date:||November 2009|
|Primary Completion Date:||November 2009 (Final data collection date for primary outcome measure)|
Exposed to an acute painful phenomenon requiring an analgesic management
Control, not exposed to acute pain
|University Hospital Toulouse|
|Toulouse, France, 31059|
|Study Director:||Maryse Lapeyre-Mestre, MD||University Hospital, Toulouse|