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Association of Thyroid Autoimmunity and Chronic Urticaria

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Ju-Ying Jiang, Far Eastern Memorial Hospital
ClinicalTrials.gov Identifier:
NCT00737451
First received: June 30, 2008
Last updated: March 26, 2012
Last verified: September 2009
  Purpose

Increase prevalence of thyroid autoimmunity is found in patients with chronic urticaria. About 5-34% of chronic urticaria patients is associated with the presence of thyroid autoimmunity who are euthyroid status whereas 5-10% of them with either hyperthyroidism or hypothyroidism.


Condition Intervention
Skin Itching
Chronic Urticaria
Behavioral: blood sampling

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Association of Thyroid Autoimmunity and Chronic Urticaria in Taiwan

Resource links provided by NLM:


Further study details as provided by Far Eastern Memorial Hospital:

Primary Outcome Measures:
  • The prevalence of thyroid autoimmunity in chronic urticaria in Taiwan [ Time Frame: one year ] [ Designated as safety issue: Yes ]

Enrollment: 155
Study Start Date: March 2008
Study Completion Date: November 2010
Primary Completion Date: November 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
skin itching Behavioral: blood sampling
blood sampling 10ml from the study subjects

Detailed Description:

There is no such report on the association of thyroid autoantibodies and chronic urticaria in Taiwan population yet. This study is designed to investigate the prevalence of thyroid autoimmunity associated with chronic urticaria in Taiwanese population. In addition, we intend to find out the change in the level of thyroid autoimmunity after the treatment in order to further understand their relationship. We also intend to find out the prognostic parameters in patients with the presence of thyroid autoimmunity and chronic urticaria.

  Eligibility

Ages Eligible for Study:   18 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Patients aged 18 and above with complaint of skin itching

Criteria

Inclusion Criteria:

  • 18 years old and above
  • skin itching for more than 6 months

Exclusion Criteria:

  • pure physical urticaria, infectious diseases, and food or food addictive hypersensitivity, chronic infection
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00737451

Locations
Taiwan
Far Eastern Memorial Hospital
Pan-Chiao, Taipei, Taiwan, 22060
Sponsors and Collaborators
Far Eastern Memorial Hospital
Investigators
Principal Investigator: Jiang Ju Ying, MD Far Eastern Memorial Hospital
  More Information

No publications provided

Responsible Party: Ju-Ying Jiang, Attending physician, Far Eastern Memorial Hospital
ClinicalTrials.gov Identifier: NCT00737451     History of Changes
Other Study ID Numbers: 96051
Study First Received: June 30, 2008
Last Updated: March 26, 2012
Health Authority: Taiwan: Institutional Review Board

Keywords provided by Far Eastern Memorial Hospital:
urticaria
goiter

Additional relevant MeSH terms:
Pruritus
Urticaria
Hypersensitivity
Hypersensitivity, Immediate
Immune System Diseases
Signs and Symptoms
Skin Diseases
Skin Diseases, Vascular
Skin Manifestations

ClinicalTrials.gov processed this record on November 20, 2014