Effects of a Computerized Physician Order Entry (CPOE)-Based Inpatient Insulin Protocol on Glycemic Outcomes

This study has been completed.
Sponsor:
Information provided by:
John H. Stroger Hospital
ClinicalTrials.gov Identifier:
NCT00718198
First received: July 16, 2008
Last updated: February 10, 2009
Last verified: February 2009
  Purpose

This study is a retrospective cross-sectional study at one institution, where the investigators compared diabetic patients admitted to Medicine Services from March-April 2006 (before CPOE was implemented) to patients admitted from October-November 2007 (one year after CPOE implementation). Capillary blood glucose values, Hemoglobin AIC, diabetes medication profile and demographic data were obtained to compare between groups. The investigators hypothesized that a computer-based protocol that emphasizes basal-bolus and correctional insulin orders and excludes sliding scale, in conjunction with nursing personnel inservicing, improves outcomes.


Condition
Diabetes Mellitus

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Effects of a Computerized Physician Order Entry (CPOE)-Based Inpatient Insulin Protocol on Glycemic Outcomes

Resource links provided by NLM:


Further study details as provided by John H. Stroger Hospital:

Primary Outcome Measures:
  • Mean Inpatient Glucose [ Time Frame: From admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Percentage of normoglycemic (70 to 150 mg/dl) patient-days [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]
  • Percentage of hyperglycemic patient-days [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]
  • Percentage of Patient-days with glucose less than 70 mg/dl [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: Yes ]
  • Percentage of Patients with inpatient or recent (less than 6 months) hemoglobin AIC [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]
  • Length of stay [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]
  • Distribution of oral hypoglycemic use [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]
  • Distribution of type of insulin therapy used [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]
  • Percent of patient-days with severe hypoglycemia [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: Yes ]

Enrollment: 413
Study Start Date: March 2006
Study Completion Date: June 2008
Primary Completion Date: December 2007 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
Group admitted 1 (one) month before CPOE protocol changes were made
2
Group admitted 1 (one) year after CPOE protocol changes were made

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Diabetic patients admitted to Medicine Services

Criteria

Inclusion Criteria:

  • Clinical diagnosis of Diabetes Mellitus

Exclusion Criteria:

  • Admitted to Non-Medicine Hospital Services
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00718198

Locations
United States, Illinois
John H. Stroger Jr. Hospital
Chicago, Illinois, United States, 60612
Sponsors and Collaborators
John H. Stroger Hospital
Investigators
Principal Investigator: Yannis S Guerra, MD Rush University Hospital/John H Stroger Jr. Hospital
Study Chair: Krishna Das, MD John H. Stroger Jr. Hospital
Study Chair: Pete Antonopoulos, MD John H. Stroger Jr. Hospital
Study Chair: Irene Benson, RN John H. Stroger Jr. Hospital
Study Chair: Shane Borkowski, MD John H. Stroger Jr. Hospital
Study Chair: Leon Fogelfeld, MD John H. Stroger Jr. Hospital
Study Chair: Melanie Gordon, MD John H. Stroger Jr. Hospital
Study Chair: Betsy Palal, MD John H. Stroger Jr. Hospital
Study Chair: Joana Witsil, MD John H. Stroger Jr. Hospital
Study Director: Evelyn Lacuesta, MD John H. Stroger Jr. Hospital
  More Information

No publications provided

Responsible Party: Yannis Guerra, Rush University Hospital/John H. Stroger Jr. Hospital of Cook County
ClinicalTrials.gov Identifier: NCT00718198     History of Changes
Other Study ID Numbers: JHSEndo01
Study First Received: July 16, 2008
Last Updated: February 10, 2009
Health Authority: United States: Institutional Review Board

Keywords provided by John H. Stroger Hospital:
Inpatient
Computer Physician Order Entry
Diabetes Mellitus

Additional relevant MeSH terms:
Diabetes Mellitus
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases

ClinicalTrials.gov processed this record on April 17, 2014