Effects of a Computerized Physician Order Entry (CPOE)-Based Inpatient Insulin Protocol on Glycemic Outcomes

This study has been completed.
Sponsor:
Information provided by:
John H. Stroger Hospital
ClinicalTrials.gov Identifier:
NCT00718198
First received: July 16, 2008
Last updated: February 10, 2009
Last verified: February 2009
  Purpose

This study is a retrospective cross-sectional study at one institution, where the investigators compared diabetic patients admitted to Medicine Services from March-April 2006 (before CPOE was implemented) to patients admitted from October-November 2007 (one year after CPOE implementation). Capillary blood glucose values, Hemoglobin AIC, diabetes medication profile and demographic data were obtained to compare between groups. The investigators hypothesized that a computer-based protocol that emphasizes basal-bolus and correctional insulin orders and excludes sliding scale, in conjunction with nursing personnel inservicing, improves outcomes.


Condition
Diabetes Mellitus

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Effects of a Computerized Physician Order Entry (CPOE)-Based Inpatient Insulin Protocol on Glycemic Outcomes

Resource links provided by NLM:


Further study details as provided by John H. Stroger Hospital:

Primary Outcome Measures:
  • Mean Inpatient Glucose [ Time Frame: From admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Percentage of normoglycemic (70 to 150 mg/dl) patient-days [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]
  • Percentage of hyperglycemic patient-days [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]
  • Percentage of Patient-days with glucose less than 70 mg/dl [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: Yes ]
  • Percentage of Patients with inpatient or recent (less than 6 months) hemoglobin AIC [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]
  • Length of stay [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]
  • Distribution of oral hypoglycemic use [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]
  • Distribution of type of insulin therapy used [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: No ]
  • Percent of patient-days with severe hypoglycemia [ Time Frame: admission to hospital until discharge from hospital ] [ Designated as safety issue: Yes ]

Enrollment: 413
Study Start Date: March 2006
Study Completion Date: June 2008
Primary Completion Date: December 2007 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
Group admitted 1 (one) month before CPOE protocol changes were made
2
Group admitted 1 (one) year after CPOE protocol changes were made

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Diabetic patients admitted to Medicine Services

Criteria

Inclusion Criteria:

  • Clinical diagnosis of Diabetes Mellitus

Exclusion Criteria:

  • Admitted to Non-Medicine Hospital Services
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00718198

Locations
United States, Illinois
John H. Stroger Jr. Hospital
Chicago, Illinois, United States, 60612
Sponsors and Collaborators
John H. Stroger Hospital
Investigators
Principal Investigator: Yannis S Guerra, MD Rush University Hospital/John H Stroger Jr. Hospital
Study Chair: Krishna Das, MD John H. Stroger Jr. Hospital
Study Chair: Pete Antonopoulos, MD John H. Stroger Jr. Hospital
Study Chair: Irene Benson, RN John H. Stroger Jr. Hospital
Study Chair: Shane Borkowski, MD John H. Stroger Jr. Hospital
Study Chair: Leon Fogelfeld, MD John H. Stroger Jr. Hospital
Study Chair: Melanie Gordon, MD John H. Stroger Jr. Hospital
Study Chair: Betsy Palal, MD John H. Stroger Jr. Hospital
Study Chair: Joana Witsil, MD John H. Stroger Jr. Hospital
Study Director: Evelyn Lacuesta, MD John H. Stroger Jr. Hospital
  More Information

No publications provided

Responsible Party: Yannis Guerra, Rush University Hospital/John H. Stroger Jr. Hospital of Cook County
ClinicalTrials.gov Identifier: NCT00718198     History of Changes
Other Study ID Numbers: JHSEndo01
Study First Received: July 16, 2008
Last Updated: February 10, 2009
Health Authority: United States: Institutional Review Board

Keywords provided by John H. Stroger Hospital:
Inpatient
Computer Physician Order Entry
Diabetes Mellitus

Additional relevant MeSH terms:
Diabetes Mellitus
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases

ClinicalTrials.gov processed this record on July 31, 2014