The Effect of Air Pollution on Lung Health Among Children Living in Haifa Bay Region, Israel
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Purpose
Haifa bay region is located close to a major industrial zone. The aim of the study is to evaluate the health status of children living in Haifa bay region.
The health status will be evaluated using health questionnaires and spirometry.
| Condition | Intervention |
|---|---|
|
Bronchial Asthma Signs and Symptoms, Respiratory Allergy |
Device: Spirometry (Pony spirometer) |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Diagnostic |
| Official Title: | The Effect of Air Pollution on Lung Health Among Children Living in Haifa Bay Region, Israel. |
- The prevalence of respiratory symptoms in respect to air pollution [ Time Frame: Two years ] [ Designated as safety issue: No ]
| Enrollment: | 15 |
| Study Start Date: | December 2008 |
| Study Completion Date: | September 2010 |
| Primary Completion Date: | August 2009 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Experimental: 1
Children at school age from Haifa bay region
|
Device: Spirometry (Pony spirometer)
Spirometry at rest
Other Name: Pony spirometer, Cosmed, Italy.
|
Detailed Description:
Haifa bay is located close to a major industrial zone. The aim of the study is to evaluate the health status of children living in Haifa bay region.
The health status will be evaluated while using health questionnaires and spirometry.
Objective: To evaluate the respiratory health of Haifa bay region children with comparatives, with respect to local air pollution levels.
Material and Methods: Children from Haifa bay region from 10 different communities (1200 children) will be included in the study, after both parents and the children (above 12 years of age) will sign an informed consent form.
First step: A health questionnaire (based on Hebrew version of ISAAC questionnaire) will be filled in by the parents.
Second step: Spirometry checking of the children. In parallel, air pollution levels will be measured and provided by a network of ground monitoring stations maintained by the Haifa District Municipality Association for the Environment (HDMAE). The station provides half-hourly measurement of mean concentrations of gaseous (NOX, SO2, O3) and particular (PM 10) pollutants over the entire investigation window. Additional meteorological data are also collected.
Risk maps: Using a GIS platform, we are developing a multi-layer risk mapping procedure which accounts for ambient concentrations of selected pollutants and the heterogenic spatial distribution of several demographic and socio-economic indexes in the region.
The prevalence of pulmonary disease will be evaluated according to the risk maps The health status of the children will be documented from the children's primary clinic files as well.
Eligibility| Ages Eligible for Study: | 6 Years to 12 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Living in Haifa bay region, Israel.
- Parents signed informed consent.
Exclusion Criteria:
- Children that their parents did not signed the informed consent
- Chronic disease except of asthma: Diabetes mellitus, Cystic Fibrosis, Cardiac diseases, Renal, Rheumatic and Chronic Gastrointestinal diseases, Mental retardation.
Contacts and Locations
More Information
No publications provided
| Responsible Party: | Haim Bibi, MD, Carmel Medical Center |
| ClinicalTrials.gov Identifier: | NCT00718133 History of Changes |
| Other Study ID Numbers: | HTA 4643/ CMC 0066-07 |
| Study First Received: | July 17, 2008 |
| Last Updated: | September 13, 2010 |
| Health Authority: | Israel: Israeli Health Ministry Pharmaceutical Administration |
Keywords provided by Carmel Medical Center:
|
Asthma Allergy Respiratory |
Pollution Children Air pollution |
Additional relevant MeSH terms:
|
Hypersensitivity Asthma Signs and Symptoms Signs and Symptoms, Respiratory Immune System Diseases Bronchial Diseases |
Respiratory Tract Diseases Lung Diseases, Obstructive Lung Diseases Respiratory Hypersensitivity Hypersensitivity, Immediate |
ClinicalTrials.gov processed this record on May 23, 2013