Studying Umbilical Cord Blood From African-American Donors
RATIONALE: Studying umbilical cord blood in the laboratory and gathering information about current and previous pregnancies from African-American umbilical cord blood donors may help doctors learn more about the umbilical cord blood of these donors.
PURPOSE: This clinical trial is looking at umbilical cord blood from African-American donors.
Health Status Unknown
Other: questionnaire administration
Other: study of socioeconomic and demographic variables
|Study Design:||Time Perspective: Prospective|
|Official Title:||Investigation of the Total Nucleated Cell Yield of Cord Blood Units Collected From African-American Donors in Correlation With Gestational and Other Health Variables|
- Correlation between total nucleated cell yield of cord blood units and gestational history, maternal history, and delivery information [ Time Frame: Within a year ] [ Designated as safety issue: No ]
- Improvement in total nucleated cell yield of cord blood units from African-American donors [ Time Frame: Within a year ] [ Designated as safety issue: No ]
Biospecimen Retention: None Retained
Cord blood unit (CBU)will be collected in utero and transported to the Stem Cell Processing Laboratory. The volume of the CBU will be measured and cell count will be obtained.
|Study Start Date:||August 2005|
|Study Completion Date:||November 2009|
|Primary Completion Date:||November 2009 (Final data collection date for primary outcome measure)|
- To correlate the total nucleated cell yield of cord blood units from African-American cord blood donors with gestational history, maternal history, and delivery information.
OUTLINE: This is a multicenter study.
Donors complete questionnaires about their demographics, maternal history, gestational history, and delivery. Cord blood units (CBU) are collected in utero and transported to the Stem Cell Processing Laboratory where they are evaluated for CBU volume and cell count (i.e., total nucleated cell yield) and cryopreserved. The study results will then be used to devise future interventional strategies to improve the yield of nucleated cells of CBU.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00717535
|Principal Investigator:||Voravit Ratanatharathorn, MD||Barbara Ann Karmanos Cancer Institute|