European Quality Improvement Programme for Acute Coronary Syndromes (EQUIP-ACS)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2008 by Royal Brompton & Harefield NHS Foundation Trust.
Recruitment status was  Recruiting
Sponsor:
Collaborators:
Uppsala Clinical Research
GlaxoSmithKline
Information provided by:
Royal Brompton & Harefield NHS Foundation Trust
ClinicalTrials.gov Identifier:
NCT00716430
First received: July 11, 2008
Last updated: July 15, 2008
Last verified: July 2008
  Purpose

The main hypothesis to be tested is that the use of a quality improvement programme will lead to measurable improvements in the management of care and use of evidence based treatments for patients presenting to hospital with non-ST elevation acute coronary syndromes.


Condition Intervention
Acute Coronary Syndrome
Behavioral: Quality Improvement Programme

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Health Services Research
Official Title: Improving the Management of Non-ST Elevation Acute Coronary Syndrome: Systematic Evaluation of a Quality Improvement Programme

Further study details as provided by Royal Brompton & Harefield NHS Foundation Trust:

Primary Outcome Measures:
  • Composite of 7 outcome measures to assess aggregate potential for improvement in care using the QI programme:1:risk stratification within 24 hrs, 2:early coronary angiography, 3:anticoagulation, 4:beta-blockers, 5:statins, 6:ACE-inhibitors, 7:Clopidogrel [ Time Frame: 10 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Clinical outcomes at discharge including death and myocardial infarction [ Time Frame: 10 months ] [ Designated as safety issue: No ]
  • Estimated costs of care for patients [ Time Frame: 10 months ] [ Designated as safety issue: No ]
  • Estimated costs and economic evaluation of potential cost-effectiveness of QI programme [ Time Frame: 10 months ] [ Designated as safety issue: No ]

Estimated Enrollment: 3500
Study Start Date: August 2007
Estimated Study Completion Date: February 2009
Estimated Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: QI
Quality Improvement Centres
Behavioral: Quality Improvement Programme
Quality Improvement training programme
No Intervention: Non-QI
No Quality Improvement Programme

  Eligibility

Ages Eligible for Study:   up to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

Patients with a good clinical history of ACS and at least one of the following:

  • New or transient ST or T wave changes on the ECG consistent with acute myocardial ischaemia
  • Elevation of troponin or other cardiac markers to levels indicative of myocardial necrosis according to local laboratory values

Exclusion Criteria:

  • Evidence of persistent ST elevation on the ECG
  • Use of early reperfusion therapy
  • Patients >80 years
  • Patients transferred from another hospital
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00716430

Contacts
Contact: Marcus D Flather 0044 (0) 207 351 8827 m.flather@rbht.nhs.uk
Contact: Daphne Babalis 0044 (0) 207 351 8889 d.babalis@rbht.nhs.uk

Locations
France
Centre Hospitalier de la region d'Annecy Recruiting
Annecy, France
Principal Investigator: Loic Belle         
Centre Hospitalier de Chambery Recruiting
Chambery, France
Principal Investigator: Christian Chaussard         
Cardiology dept. B, CHU Hopital G. Montpied Recruiting
Clermont Ferrand, France
Principal Investigator: Bernard Citron         
CHU de Grenoble Recruiting
Grenoble, France
Principal Investigator: Gerald Vanzetto         
Centre Hospitalier de Riom Guy Thomas Recruiting
Riom, France
Principal Investigator: Laurence Flork         
Hopitaux Drome Nord de Romans-sur-Isere Recruiting
Romans-sur-Isere, France
Principal Investigator: Christian Chaussard         
Centre Hospitalier d'Ussel Recruiting
Ussel, France
Principal Investigator: Alain Berenfeld         
Centre Hospitalier Pierre Bazin Recruiting
Voiron, France
Principal Investigator: Hubert Mann         
Italy
Ospedale M. Bufalini Recruiting
Cesena, Italy
Principal Investigator: Flavio Tartagni         
Ospedale Morgagni-Pierantoni Recruiting
Forli, Italy
Principal Investigator: Filippo Ottani         
Ospedale di Livorno Recruiting
Livorno, Italy
Principal Investigator: Michele Galli         
Ospedale Generale Provinciale di Macerata Recruiting
Macerata, Italy
Principal Investigator: Gian Luigi Morgagni         
Ospedale Civile di Mirano Recruiting
Mirano, Italy
Principal Investigator: Luca Favero         
Poland
Szpital w Ciechanowie Recruiting
Ciechanow, Poland
Principal Investigator: Bogdan Zbyszynski         
Szpital Zachodni Recruiting
Grodzisk Mazowiecki, Poland
Principal Investigator: Marek Stopinski         
Szpital w Grojcu Recruiting
Grojec, Poland
Principal Investigator: Zbigniew Binio         
Swietofrzyskie Centrum Chorob Serca Recruiting
Kielce, Poland
Principal Investigator: Marianna Janion         
Szpital w Plocku Recruiting
Plock, Poland
Principal Investigator: Maciej Rynkiewicz         
Szpital Specjalistyczny SPZOZ w Radom Recruiting
Radom, Poland
Principal Investigator: Bozena Wrzosek         
Radomski Szpital Specjalistyczny Recruiting
Radom, Poland
Principal Investigator: Piotr Achremczyk         
Szpital w Siedlcach Recruiting
Siedlce, Poland
Principal Investigator: Piotr Kolodziej         
SP CSK- Medical University of Warsaw Recruiting
Warsaw, Poland
Principal Investigator: Grzegorz Opolski         
Szpital we Wloclawku Recruiting
Wloclawek, Poland
Principal Investigator: Jerzy Kopaczewski         
Spain
Hospital Universitario Germans Trias Recruiting
Badalona, Spain
Principal Investigator: Antonio Curos Abadal         
Hospital Universitario Vall d'Hebron Recruiting
Barcelona, Spain
Principal Investigator: Jose Barrabes         
Hospital del Mar Recruiting
Barcelona, Spain
Principal Investigator: Lluis Recasens Gracia         
Hospital Josep Trueta Recruiting
Girona, Spain
Principal Investigator: Joan Sala         
Hospital Universitario Joan XXIII Recruiting
Tarragona, Spain
Principal Investigator: Ramon de Castro         
Hospital de Terrassa Recruiting
Terrassa-Barcelona, Spain
Principal Investigator: Antonio Sanchez Hidalgo         
Hospital de Tortosa Virgen de la Cinta Recruiting
Tortosa, Spain
Principal Investigator: David Bierge Valero         
United Kingdom
Antrim Area Hospital Recruiting
Antrim, United Kingdom
Principal Investigator: Thomas Trouton         
Barnet General Hospital Recruiting
Barnet, United Kingdom
Principal Investigator: Ameet Bakhai         
Basildon Hospital Recruiting
Essex, United Kingdom
Principal Investigator: Rajesh Aggarwal         
Warwick Hospital Recruiting
Warwick, United Kingdom
Principal Investigator: Najmi Qureshi         
Royal Albert Edward Infirmary Recruiting
Wigan, United Kingdom
Principal Investigator: Sanjay Arya         
Yeovil District Hospital Recruiting
Yeovil, United Kingdom
Principal Investigator: George Chung         
York District Hospital Recruiting
York, United Kingdom
Principal Investigator: Maurice Pye         
Sponsors and Collaborators
Royal Brompton & Harefield NHS Foundation Trust
Uppsala Clinical Research
GlaxoSmithKline
  More Information

No publications provided by Royal Brompton & Harefield NHS Foundation Trust

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Dr Marcus Flather, Royal Brompton Hospital
ClinicalTrials.gov Identifier: NCT00716430     History of Changes
Other Study ID Numbers: EQUIP-ACS 1
Study First Received: July 11, 2008
Last Updated: July 15, 2008
Health Authority: United Kingdom: Research Ethics Committee
France: Comite d'Ethique des Centres d'Investigation Clinique
Spain: Comité Ético de Investigación Clínica
Italy: National Ethics Committee
Poland: Komisja Bioetyczna

Keywords provided by Royal Brompton & Harefield NHS Foundation Trust:
acute coronary syndromes
quality improvement

Additional relevant MeSH terms:
Acute Coronary Syndrome
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Angina Pectoris
Vascular Diseases
Chest Pain
Pain
Signs and Symptoms

ClinicalTrials.gov processed this record on April 15, 2014