European Quality Improvement Programme for Acute Coronary Syndromes (EQUIP-ACS)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2008 by Royal Brompton & Harefield NHS Foundation Trust.
Recruitment status was  Recruiting
Sponsor:
Collaborators:
Uppsala University
GlaxoSmithKline
Information provided by:
Royal Brompton & Harefield NHS Foundation Trust
ClinicalTrials.gov Identifier:
NCT00716430
First received: July 11, 2008
Last updated: July 15, 2008
Last verified: July 2008
  Purpose

The main hypothesis to be tested is that the use of a quality improvement programme will lead to measurable improvements in the management of care and use of evidence based treatments for patients presenting to hospital with non-ST elevation acute coronary syndromes.


Condition Intervention
Acute Coronary Syndrome
Behavioral: Quality Improvement Programme

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Health Services Research
Official Title: Improving the Management of Non-ST Elevation Acute Coronary Syndrome: Systematic Evaluation of a Quality Improvement Programme

Further study details as provided by Royal Brompton & Harefield NHS Foundation Trust:

Primary Outcome Measures:
  • Composite of 7 outcome measures to assess aggregate potential for improvement in care using the QI programme:1:risk stratification within 24 hrs, 2:early coronary angiography, 3:anticoagulation, 4:beta-blockers, 5:statins, 6:ACE-inhibitors, 7:Clopidogrel [ Time Frame: 10 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Clinical outcomes at discharge including death and myocardial infarction [ Time Frame: 10 months ] [ Designated as safety issue: No ]
  • Estimated costs of care for patients [ Time Frame: 10 months ] [ Designated as safety issue: No ]
  • Estimated costs and economic evaluation of potential cost-effectiveness of QI programme [ Time Frame: 10 months ] [ Designated as safety issue: No ]

Estimated Enrollment: 3500
Study Start Date: August 2007
Estimated Study Completion Date: February 2009
Estimated Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: QI
Quality Improvement Centres
Behavioral: Quality Improvement Programme
Quality Improvement training programme
No Intervention: Non-QI
No Quality Improvement Programme

  Eligibility

Ages Eligible for Study:   up to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

Patients with a good clinical history of ACS and at least one of the following:

  • New or transient ST or T wave changes on the ECG consistent with acute myocardial ischaemia
  • Elevation of troponin or other cardiac markers to levels indicative of myocardial necrosis according to local laboratory values

Exclusion Criteria:

  • Evidence of persistent ST elevation on the ECG
  • Use of early reperfusion therapy
  • Patients >80 years
  • Patients transferred from another hospital
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00716430

Contacts
Contact: Marcus D Flather 0044 (0) 207 351 8827 m.flather@rbht.nhs.uk
Contact: Daphne Babalis 0044 (0) 207 351 8889 d.babalis@rbht.nhs.uk

Locations
France
Centre Hospitalier de la region d'Annecy Recruiting
Annecy, France
Principal Investigator: Loic Belle         
Centre Hospitalier de Chambery Recruiting
Chambery, France
Principal Investigator: Christian Chaussard         
Cardiology dept. B, CHU Hopital G. Montpied Recruiting
Clermont Ferrand, France
Principal Investigator: Bernard Citron         
CHU de Grenoble Recruiting
Grenoble, France
Principal Investigator: Gerald Vanzetto         
Centre Hospitalier de Riom Guy Thomas Recruiting
Riom, France
Principal Investigator: Laurence Flork         
Hopitaux Drome Nord de Romans-sur-Isere Recruiting
Romans-sur-Isere, France
Principal Investigator: Christian Chaussard         
Centre Hospitalier d'Ussel Recruiting
Ussel, France
Principal Investigator: Alain Berenfeld         
Centre Hospitalier Pierre Bazin Recruiting
Voiron, France
Principal Investigator: Hubert Mann         
Italy
Ospedale M. Bufalini Recruiting
Cesena, Italy
Principal Investigator: Flavio Tartagni         
Ospedale Morgagni-Pierantoni Recruiting
Forli, Italy
Principal Investigator: Filippo Ottani         
Ospedale di Livorno Recruiting
Livorno, Italy
Principal Investigator: Michele Galli         
Ospedale Generale Provinciale di Macerata Recruiting
Macerata, Italy
Principal Investigator: Gian Luigi Morgagni         
Ospedale Civile di Mirano Recruiting
Mirano, Italy
Principal Investigator: Luca Favero         
Poland
Szpital w Ciechanowie Recruiting
Ciechanow, Poland
Principal Investigator: Bogdan Zbyszynski         
Szpital Zachodni Recruiting
Grodzisk Mazowiecki, Poland
Principal Investigator: Marek Stopinski         
Szpital w Grojcu Recruiting
Grojec, Poland
Principal Investigator: Zbigniew Binio         
Swietofrzyskie Centrum Chorob Serca Recruiting
Kielce, Poland
Principal Investigator: Marianna Janion         
Szpital w Plocku Recruiting
Plock, Poland
Principal Investigator: Maciej Rynkiewicz         
Szpital Specjalistyczny SPZOZ w Radom Recruiting
Radom, Poland
Principal Investigator: Bozena Wrzosek         
Radomski Szpital Specjalistyczny Recruiting
Radom, Poland
Principal Investigator: Piotr Achremczyk         
Szpital w Siedlcach Recruiting
Siedlce, Poland
Principal Investigator: Piotr Kolodziej         
SP CSK- Medical University of Warsaw Recruiting
Warsaw, Poland
Principal Investigator: Grzegorz Opolski         
Szpital we Wloclawku Recruiting
Wloclawek, Poland
Principal Investigator: Jerzy Kopaczewski         
Spain
Hospital Universitario Germans Trias Recruiting
Badalona, Spain
Principal Investigator: Antonio Curos Abadal         
Hospital Universitario Vall d'Hebron Recruiting
Barcelona, Spain
Principal Investigator: Jose Barrabes         
Hospital del Mar Recruiting
Barcelona, Spain
Principal Investigator: Lluis Recasens Gracia         
Hospital Josep Trueta Recruiting
Girona, Spain
Principal Investigator: Joan Sala         
Hospital Universitario Joan XXIII Recruiting
Tarragona, Spain
Principal Investigator: Ramon de Castro         
Hospital de Terrassa Recruiting
Terrassa-Barcelona, Spain
Principal Investigator: Antonio Sanchez Hidalgo         
Hospital de Tortosa Virgen de la Cinta Recruiting
Tortosa, Spain
Principal Investigator: David Bierge Valero         
United Kingdom
Antrim Area Hospital Recruiting
Antrim, United Kingdom
Principal Investigator: Thomas Trouton         
Barnet General Hospital Recruiting
Barnet, United Kingdom
Principal Investigator: Ameet Bakhai         
Basildon Hospital Recruiting
Essex, United Kingdom
Principal Investigator: Rajesh Aggarwal         
Warwick Hospital Recruiting
Warwick, United Kingdom
Principal Investigator: Najmi Qureshi         
Royal Albert Edward Infirmary Recruiting
Wigan, United Kingdom
Principal Investigator: Sanjay Arya         
Yeovil District Hospital Recruiting
Yeovil, United Kingdom
Principal Investigator: George Chung         
York District Hospital Recruiting
York, United Kingdom
Principal Investigator: Maurice Pye         
Sponsors and Collaborators
Royal Brompton & Harefield NHS Foundation Trust
Uppsala University
GlaxoSmithKline
  More Information

No publications provided by Royal Brompton & Harefield NHS Foundation Trust

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Dr Marcus Flather, Royal Brompton Hospital
ClinicalTrials.gov Identifier: NCT00716430     History of Changes
Other Study ID Numbers: EQUIP-ACS 1
Study First Received: July 11, 2008
Last Updated: July 15, 2008
Health Authority: United Kingdom: Research Ethics Committee
France: Comite d'Ethique des Centres d'Investigation Clinique
Spain: Comité Ético de Investigación Clínica
Italy: National Ethics Committee
Poland: Komisja Bioetyczna

Keywords provided by Royal Brompton & Harefield NHS Foundation Trust:
acute coronary syndromes
quality improvement

Additional relevant MeSH terms:
Acute Coronary Syndrome
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Angina Pectoris
Vascular Diseases
Chest Pain
Pain
Signs and Symptoms

ClinicalTrials.gov processed this record on July 22, 2014