Infrastructure for Developing Gastrointestinal Cancer Prognostic and Predictive Markers
This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
Haematology-Oncology, National University Hospital, Singapore
First received: July 14, 2008
Last updated: March 3, 2014
Last verified: March 2014
The proposal seeks to establish:
- A comprehensive compilation (database) of clinical information comprising clinical, histopathological, treatment and follow-up characteristics of past and future gastrointestinal cancer (GIC) cases in Singapore that can be shared by investigators. The characteristics will include clinical (eg age, sex, stage), histopathological (eg. grade, type), treatment (eg. treatment status, regimens) and outcome data (eg. survival, toxicity) from medical records.
- A collection (bank) of corresponding frozen and fixed tissue, blood and processed samples (enriched blood mononuclear cells, protein, RNA, DNA, tissue arrays) in Singapore that can be shared by the investigators.
- A gastrointestinal cancer co-operative group (GCCG) of clinicians and scientists researching prognostic and predictive markers in GIC, which will benefit from the multi-disciplinary knowledge, information and samples of its members.
- To characterise genetic polymorphisms related to Gastrointestinal cancer chemotherapy treatment in controls (healthy volunteers)
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Infrastructure for Developing Gastrointestinal Cancer Prognostic and Predictive Markers|
Resource links provided by NLM:
Further study details as provided by National University Hospital, Singapore:
|Study Start Date:||September 2012|
|Estimated Primary Completion Date:||December 2014 (Final data collection date for primary outcome measure)|
Patients with cancers of the gastrointestinal tract (eg. colorectal, gastric, pancreatic, esophageal)
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00716209
|National University Hospital|
Sponsors and Collaborators
|Principal Investigator:||Ross Andrew Soo, MBBS||National University Hospital, Singapore|
|Principal Investigator:||Alex Chang||Johns Hopkins University|
|Principal Investigator:||Chung Yip Chan||Tan Tock Seng Hospital|