Speech and Language Therapy After Stroke

This study is ongoing, but not recruiting participants.

First Received on July 9, 2008. Last Updated on July 13, 2011 History of Changes

Sponsor:	University of Chicago
Collaborators:	National Institute on Deafness and Other Communication Disorders (NIDCD) Rehabilitation Institute of Chicago
Information provided by:	University of Chicago
ClinicalTrials.gov Identifier:	NCT00713050

Purpose

Our overall goal is to advance the state of functional brain imaging in aphasia, and then to apply the method to an intensive, imitation-based treatment for non-fluent aphasia.

Condition	Intervention
Ischemic Stroke	Behavioral: Imitate Therapy

Study Type:	Interventional
Study Design:	Allocation: Randomized Intervention Model: Single Group Assignment Masking: Double Blind (Subject, Outcomes Assessor) Primary Purpose: Treatment
Official Title:	Neurophysiological Measurement in Aphasia Treatment

Resource links provided by NLM:

MedlinePlus related topics: Aphasia

U.S. FDA Resources

Further study details as provided by University of Chicago:

Primary Outcome Measures:

Changes in scores on Western Aphasia Battery [ Time Frame: Four months ] [ Designated as safety issue: No ]

Estimated Enrollment:	57
Study Start Date:	August 2007
Estimated Study Completion Date:	August 2013
Estimated Primary Completion Date:	August 2013 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Experimental: Experimental Experimental Arm	Behavioral: Imitate Therapy Imitation-based computer therapy Other Name: Imitate
Active Comparator: Control Control Arm	Behavioral: Imitate Therapy Imitation-based computer therapy Other Name: Imitate

Detailed Description:

Detailed information will follow in the next progress report.

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Single ischemic infarction in the MCA territory involving the cerebral cortex (confirmed by CT or MRI)
Aphasia
Visual attention and language comprehension sufficient to perform imitation fMRI tasks
Right handed (prior to stroke)

Exclusion Criteria:

Exclusions to the study are people with cardiac pacemakers, claustrophobia, neurosurgical clips, or cognitive impairments too severe to permit cooperation with cognitive tasks in an MRI scanner.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00713050

Locations

United States, Illinois
University of Chicago
Chicago, Illinois, United States, 60637
Rehabilitation Institute of Chicago
Chicago, Illinois, United States, 60611

Sponsors and Collaborators

University of Chicago

National Institute on Deafness and Other Communication Disorders (NIDCD)

Rehabilitation Institute of Chicago

Investigators

Principal Investigator:

Steven Small, M.D., Ph.D.

University of Chicago

More Information

No publications provided

Responsible Party:	Dr. Steven Small, M.D., Ph.D. /Professor, University of Chicago
ClinicalTrials.gov Identifier:	NCT00713050 History of Changes
Other Study ID Numbers:	13785A, 5R01DC007488-05
Study First Received:	July 9, 2008
Last Updated:	July 13, 2011
Health Authority:	United States: Federal Government

Keywords provided by University of Chicago:

stroke
aphasia
imitation
mirror neuron

Additional relevant MeSH terms:

Stroke
Cerebral Infarction
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases

Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases
Brain Infarction
Brain Ischemia

ClinicalTrials.gov processed this record on February 12, 2012