Effect of Montelukast on Basophils, In-vitro
Recruitment status was Active, not recruiting
Subjects with either allergic asthma or allergic rhinitis will be recruited to obtain blood. This blood will be used to be stimulated with to whatever the patient allergic. In the laboratory, this stimulated blood will be measured for histamine, leukotrienes, IL-13 and IL-3. These are chemicals responsible for allergy symptoms.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||The Effect of Montelukast In-vitro on Basophil Histamine and Leukotriene, IL-4 Adn IL-13 Release in Subjects With Allergic Rhinitis or Allergic Asthma|
- Histamine Release [ Time Frame: during the assay portion. ] [ Designated as safety issue: No ]
- Cytokine release. IL-13, IL-4 and leukotriene [ Time Frame: assay portion ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples Without DNA
Supernatents from stimulation assays will be kept for batch assay.
|Study Start Date:||May 2008|
|Estimated Study Completion Date:||September 2011|
|Estimated Primary Completion Date:||September 2011 (Final data collection date for primary outcome measure)|