Linear and Non-linear Analysis of EEG Changes in Schizophrenia After Atypical Antipsychotics Medication
Recruitment status was Active, not recruiting
The purpose of this study is to evaluate clinical meaning of EEG changes in antipsychotic-treated patients with schizophrenia.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Study of the Relationship Between EEG and Clinical Changes in Drug-Naive or Drug-Free Patients With Schizophrenia After Atypical Antipsychotic Treatment Based on Linear and Non-Linear EEG Analysis|
routine lab for changes in medical condition
|Study Start Date:||September 2004|
|Estimated Study Completion Date:||September 2010|
Electroencephalographic (EEG) changes are abundant in patients receiving antipsychotic treatment. However, studies on the meaning of these changes are rare. The results of traditional analyses based on linear methodologies were inconsistent and hard to interpret. Therefore, non-linear analyses of EEG may provide additional information in evaluating antipsychotic-induced changes in EEG.
In this study, we hypothesized that linear and non-linear EEG changes in patients with schizophrenia may be valuable in predicting treatment outcome. We also hypothesized that the assessment of other psychotic symptoms and side effects of antipsychotics may provide additional information in interpreting the results of EEG analyses.
|Korea, Republic of|
|Yong-in Mental Hospital|
|Yongin City, Gyeonggi-Do, Korea, Republic of, 446-769|
|Principal Investigator:||Yong Sik Kim, MD, PhD||Seoul National University Hospital|