Genetics of Symptomatology and Treatment Response in Psychotic Major Depression

The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2008 by Stanford University.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Stanford University
ClinicalTrials.gov Identifier:
NCT00691535
First received: June 3, 2008
Last updated: June 4, 2008
Last verified: June 2008
  Purpose

We hope to learn more about the biology of psychiatric illness with the hope of improving the diagnosis and treatment of such psychiatric conditions as major depression.


Condition
Psychotic Disorders
Depressive Disorder
Depressive Disorder, Major

Study Type: Observational
Official Title: Association of BDNF, COMT, MDRI, CRH, CRF, and GC Receptor Genetic Polymorphisms With Symptomatology and Treatment Response in Psychotic Major Depression

Resource links provided by NLM:


Further study details as provided by Stanford University:

Estimated Enrollment: 500
Study Start Date: October 2003
Detailed Description:

From the blood sample you donate, the researchers will obtain DNA. This DNA will be used to search for DNA markers related to the underlying biology of psychiatric illness and how this might explain the symptoms of these disorders. Research using DNA is an important way to try to understand human disease and/or the role genes play in disease. In effect, part of your blood sample will be used to attempt to understand how genetic factors contribute to the symptoms of such psychiatric conditions as major depression.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  1. You are currently experiencing symptoms that are consistent with an episode of major depression without symptoms of psychosis (such as hallucinations, delusions or disorder of thought process), or
  2. You are currently experiencing symptoms that are consistent with an episode of major depression with symptoms of psychosis (such as hallucinations, delusions or disorder of thought process), or
  3. You have been diagnosed with either schizophrenia or schizoaffective disorder, or
  4. You are a volunteer without a history of psychiatric illness (a healthy control subject).
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00691535

Contacts
Contact: Gregory H Cohen, MSW (650) 723-3305 ghcohen@stanford.edu

Locations
United States, California
Stanford University School of Medicine Recruiting
Stanford, California, United States, 94305
Contact: Gregory H Cohen, MSW    650-723-3305    ghcohen@stanford.edu   
Principal Investigator: Anna Lembke         
Sub-Investigator: Alan Schatzberg         
Sub-Investigator: Greer Murphy         
Sponsors and Collaborators
Stanford University
Investigators
Sub-Investigator: Alan Schatzberg Stanford University
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00691535     History of Changes
Other Study ID Numbers: SU-05132008-1160
Study First Received: June 3, 2008
Last Updated: June 4, 2008
Health Authority: USA:Institutional Review Board

Additional relevant MeSH terms:
Depression
Depressive Disorder
Depressive Disorder, Major
Mental Disorders
Psychotic Disorders
Disease
Behavioral Symptoms
Mood Disorders
Schizophrenia and Disorders with Psychotic Features
Pathologic Processes

ClinicalTrials.gov processed this record on October 19, 2014