Use of Functional Magnetic Resonance Imaging (fMRI) to Study Brain Activation in Children With Irritable Bowel Syndrome
The purpose of the study is to map regions of brain activation following rectal stimulation in children with irritable bowel syndrome (IBS) and healthy controls.
Irritable Bowel Syndrome
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Use of Functional Magnetic Resonance Imaging (fMRI) to Study Brain Activation Following Rectal Stimulation in Children With Irritable Bowel Syndrome|
- We intend to measure the degree of brain activation following rectal stimulation [ Time Frame: 4 years ] [ Designated as safety issue: No ]
|Study Start Date:||June 2007|
|Estimated Study Completion Date:||January 2014|
|Estimated Primary Completion Date:||August 2013 (Final data collection date for primary outcome measure)|
Children between the ages of 10 and 18 who meet Rome III criteria for IBS as determined by a pediatric gastroenterologist.
Healthy children between the ages of 10 and 18.
Our first aim is to compare the brain areas activated rectal stimulation in boys and girls with IBS and healthy children. Our second aim is to compare the anatomic regions of the brain activated during rectal stimulation in pre and post-pubertal male and female subjects between 10-18 yrs of age.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00677976
|United States, Wisconsin|
|Medical College of Wisconsin|
|Milwaukee, Wisconsin, United States, 53226|
|Principal Investigator:||Manu Sood, MD||Medical College of Wisconsin|