Matrix Metalloproteinase (MMP) in Heart Failure
This study has been completed.
Sponsor:
Tottori University Hospital
Information provided by:
Tottori University Hospital
ClinicalTrials.gov Identifier:
NCT00663494
First received: April 18, 2008
Last updated: July 20, 2011
Last verified: April 2008
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Purpose
The purpose of this study is to evaluate the production of MMP in failing hearts.
| Condition |
|---|
|
Chronic Stable Heart Failure |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Prospective |
| Official Title: | MMP is Produced in Failing Hearts |
Resource links provided by NLM:
Further study details as provided by Tottori University Hospital:
Primary Outcome Measures:
- MMPs level of coronary sinus
| Estimated Enrollment: | 22 |
| Study Start Date: | February 2003 |
| Study Completion Date: | July 2006 |
Myocardial fibrosis is observed in failing hearts and parallel to the progression of chronic heart failure (CHF) and myocardial remodeling. Matrix metalloproteinases (MMPs) are considered markers of fibrosis. Recently, circulating MMPs can be measured and are elevated in patients with CHF. However, MMPs it is still unclear whether MMPs are produced in failing hearts. Thus, the purpose of this study is to evaluate the production of MMP in failing hearts.
Eligibility| Genders Eligible for Study: | Both |
| Sampling Method: | Non-Probability Sample |
Study Population
chronic heart failure
Criteria
Inclusion Criteria:
- chronic stable heart failure
Contacts and Locations
No Contacts or Locations Provided
More Information
No publications provided
| Responsible Party: | Kazuhide Ogino, Tottori University Hospital |
| ClinicalTrials.gov Identifier: | NCT00663494 History of Changes |
| Other Study ID Numbers: | #244 |
| Study First Received: | April 18, 2008 |
| Last Updated: | July 20, 2011 |
| Health Authority: | Japan: Ministry of Health, Labor and Welfare |
Keywords provided by Tottori University Hospital:
|
heart failure MMP coronary sinus |
Additional relevant MeSH terms:
|
Heart Failure Heart Diseases Cardiovascular Diseases |
ClinicalTrials.gov processed this record on May 23, 2013