Matrix Metalloproteinase (MMP) in Heart Failure
The purpose of this study is to evaluate the production of MMP in failing hearts.
Chronic Stable Heart Failure
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||MMP is Produced in Failing Hearts|
- MMPs level of coronary sinus
|Study Start Date:||February 2003|
|Study Completion Date:||July 2006|
Myocardial fibrosis is observed in failing hearts and parallel to the progression of chronic heart failure (CHF) and myocardial remodeling. Matrix metalloproteinases (MMPs) are considered markers of fibrosis. Recently, circulating MMPs can be measured and are elevated in patients with CHF. However, MMPs it is still unclear whether MMPs are produced in failing hearts. Thus, the purpose of this study is to evaluate the production of MMP in failing hearts.