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Effective High Aerobic Intensity Endurance Training Regimes in Chronic Obstructive Pulmonary Disease (COPD) Patients

This study has been completed.
Sponsor:
Information provided by:
Norwegian University of Science and Technology
ClinicalTrials.gov Identifier:
NCT00658853
First received: April 10, 2008
Last updated: April 14, 2008
Last verified: April 2008
History of Changes
  Purpose

4 times 4 minutes interval training with and without hyperoxia is more effective than low intensity endurance training.


Condition Intervention
Pulmonary Disease, Chronic Obstructive
Hyperoxia
 Behavioral: 4 times 4 minutes high aerobic intensity one leg cycling

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Effective High Aerobic Intensity Interval Training to Improve Maximal Oxygen Uptake in COPD Patients

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Norwegian University of Science and Technology:

Primary Outcome Measures:
  • VO2peak [ Time Frame: 10 weeks ] [ Designated as safety issue: No ]
  • Ventilation [ Time Frame: 10 weeks ] [ Designated as safety issue: No ]
  • FEV1 [ Time Frame: 10 weeks ] [ Designated as safety issue: No ]
  • Walking performance [ Time Frame: 10 weeks ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Quality of life [ Time Frame: 3 months ] [ Designated as safety issue: No ]
  • SPSS [ Time Frame: 3 months ] [ Designated as safety issue: No ]

Enrollment: 26
Study Start Date: January 2004
Study Completion Date: February 2006
Primary Completion Date: February 2006 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: 1
High aerobic intensity treadmill walking. 4 by 4 minutes interval training on a 5% graded treadmill at a heart rate corresponding to 85-95% of maximal heart rate. 3 times per week for 10 weeks.
 Behavioral: 4 times 4 minutes high aerobic intensity one leg cycling
3 times per week for 10 weeks
Active Comparator: 2
4 times 4 minutes interval training in hyperoxia - 100% oxygen
 Behavioral: 4 times 4 minutes high aerobic intensity one leg cycling
3 times per week for 10 weeks
Active Comparator: 3
One leg at a time training 4 times 4 minutes interval training using cycling ergometer
 Behavioral: 4 times 4 minutes high aerobic intensity one leg cycling
3 times per week for 10 weeks

  Eligibility

Ages Eligible for Study:   20 Years to 85 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • COPD

Exclusion Criteria:

  • Heart disease
  • Walking or cycling inabilities
  • Other diseases
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00658853

Locations
Norway
Norwegian University of Science and Technology
Trondheim, Norway, NO-7489
Sponsors and Collaborators
Norwegian University of Science and Technology
Investigators
Principal Investigator: Jan Helgerud, PhD Norwegian University of Science and Technology
  More Information

No publications provided

Responsible Party: Professor Jan Helgerud / Assoc. Prfessor Sigurd Steinshamn, Norwegian University of Science and Technology
ClinicalTrials.gov Identifier: NCT00658853     History of Changes
Other Study ID Numbers: 149-03
Study First Received: April 10, 2008
Last Updated: April 14, 2008
Health Authority: Norway: Norwegian Social Science Data Services

Keywords provided by Norwegian University of Science and Technology:
COPD
training
VO2peak
performance
 ventilation
high aerobic intensity treadmill walking
one leg training by cycling

Additional relevant MeSH terms:
Chronic Disease
Lung Diseases
Respiration Disorders
Pulmonary Disease, Chronic Obstructive
Hyperoxia
Lung Diseases, Obstructive
 Disease Attributes
Pathologic Processes
Respiratory Tract Diseases
Signs and Symptoms, Respiratory
Signs and Symptoms

ClinicalTrials.gov processed this record on June 18, 2013