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Mitral Valve Area Assessment: Comparison With Transthoracic Echocardiography and Magnetic Resonance Imaging

The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2008 by Florence Nightingale Hospital, Istanbul.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Florence Nightingale Hospital, Istanbul
ClinicalTrials.gov Identifier:
NCT00654472
First received: April 2, 2008
Last updated: April 7, 2008
Last verified: April 2008
History of Changes
  Purpose

To compare mitral valve area in rheumatic mitral valve stenosis with cardiac magnetic resonance imaging and conventional transthoracic echocardiography.


Condition
Mitral Valve Stenosis

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Quantification of Rheumatic Mitral Stenosis With Cardiac Magnetic Resonance Imaging and Comparison With Transthoracic Echocardiography

Resource links provided by NLM:

MedlinePlus related topics: MRI Scans
U.S. FDA Resources

Further study details as provided by Florence Nightingale Hospital, Istanbul:

Estimated Enrollment: 30
Study Start Date: April 2008
Estimated Study Completion Date: June 2008
Estimated Primary Completion Date: June 2008 (Final data collection date for primary outcome measure)
Groups/Cohorts
A
Mitral valve area above 1.5 cm2
B
Mitral valve area 1.5 cm2 and below 1.5 cm2

Detailed Description:

Clinical assessment of severity of mitral stenosis depends on both the presence of symptoms and mitral valve area . Evaluation of mitral valve area with transthoracic echocardiography maintains rapid, accurate analysis of valve disease and serves as a practical gold standard for clinical evaluation. Cardiac magnetic resonance imaging (CMRI) is a recently used method that allows to evaluate cardiac structures and function noninvasively. Direct visualization of valve area with CMRI is also possible and it has been shown that the valve area assessed by CMRI planimetry correlates reliably with the invasive assessment. Velocity-encoded cardiac magnetic resonance imaging can be used to quantify mitral valve area. The objective of this study was to evaluate mitral valve area with CMRI and compare it with echocardiographic methods including 2D planimetry, Doppler continuation equation and Doppler pressure half-time

  Eligibility

Ages Eligible for Study:   20 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

tertiary care clinic

Criteria

Inclusion Criteria:

  • rheumatic mitral valve stenosis

Exclusion Criteria:

  • Degenerative mitral valve disease
  • EF<50%
  • atrial fibrillation
  • inconclusive planimetric assessment
  • moderate or severe mitral regurgitation
  • moderate or severe aortic regurgitation
  • history of previous mitral valve commissurotomy or balloon valvotomy
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00654472

Contacts
Contact: Saide Aytekin, Professor 00902122244950 ext 4038 saideaytekin@gmail.com
Contact: Özlem Yıldırımtürk, Professor 00902122244950 ext 4020 ozlemyt@gmail.com

Locations
Turkey
TC.Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology Recruiting
Istanbul, Turkey, 34381
Contact: Saide Aytekin, Professor     00902122244950 ext 4038     saideaytekin@gmail.com    
Sub-Investigator: Özlem Yıldırımtürk, MD            
Principal Investigator: Saide Aytekin, Professor            
Sub-Investigator: Aylin Tuğcu, MD            
Sub-Investigator: Yelda Tayyareci, MD            
Sub-Investigator: Onur Levent Ulusoy, MD            
Sub-Investigator: Cihan Duran, MD            
Sub-Investigator: Mustafa Şirvancı, MD            
Florence Nightinngale Hospital Recruiting
Istanbul, Turkey, 34381
Contact: Saide Ayetkin, Professor     00902122244950 ext 4038     saideaytekin@gmail.com    
Contact: Özlem Yıldırımtürk, MD     00902122244950 ext 4020     ozlemyt@gmail.com    
Sponsors and Collaborators
Florence Nightingale Hospital, Istanbul
Investigators
Study Director: Saide Aytekin, Professor T.C. Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology
  More Information

Publications:

Responsible Party: Prof. Dr. Saide Aytekin, T.C. Istanbul Bilim University, Florence Nightingale Hospital
ClinicalTrials.gov Identifier: NCT00654472     History of Changes
Other Study ID Numbers: OY1975
Study First Received: April 2, 2008
Last Updated: April 7, 2008
Health Authority: Turkey:Ministry of Health; Turkey: Ethics Commitee

Keywords provided by Florence Nightingale Hospital, Istanbul:
magnetic resonance imaging, mitral valve area

Additional relevant MeSH terms:
Constriction, Pathologic
Mitral Valve Stenosis
Pathological Conditions, Anatomical
 Heart Valve Diseases
Heart Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on June 18, 2013