Exercise and Muscle Protein Signalling

This study has been withdrawn prior to enrollment.
(A paper on the same topic came out just before we wanted to start our study.)
Sponsor:
Information provided by:
Maastricht University Medical Center
ClinicalTrials.gov Identifier:
NCT00653679
First received: April 1, 2008
Last updated: February 16, 2009
Last verified: February 2009
  Purpose

This study examines the muscle protein signalling response after resistance and endurance exercise. We hypothesize that the signalling response after endurance and resistance exercise will be partly similar.


Condition Intervention
Muscle Protein Synthesis
Other: exercise

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Basic Science
Official Title: The Impact of Resistance Versus Endurance Exercise on the Muscle Protein Signalling Response

Resource links provided by NLM:


Further study details as provided by Maastricht University Medical Center:

Primary Outcome Measures:
  • The difference in phosphorylation of different signalling proteins in the cascade towards protein synthesis [ Time Frame: 1 day ] [ Designated as safety issue: No ]

Estimated Enrollment: 15
Study Start Date: September 2008
Estimated Study Completion Date: February 2009
Estimated Primary Completion Date: February 2009 (Final data collection date for primary outcome measure)
Intervention Details:
    Other: exercise
    1 hour of endurance or resistance exercise
  Eligibility

Ages Eligible for Study:   18 Years to 28 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • healthy men
  • inactive

Exclusion Criteria:

  • enrolled in a endurance and/or resistance training program
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00653679

Locations
Netherlands
Maastricht University
Maastricht, Limburg, Netherlands, 6200 MD
Sponsors and Collaborators
Maastricht University Medical Center
Investigators
Principal Investigator: L.J.C van Loon, PhD Maastricht University
  More Information

No publications provided

Responsible Party: L.J.C van Loon, Maastricht University
ClinicalTrials.gov Identifier: NCT00653679     History of Changes
Other Study ID Numbers: MEC0001
Study First Received: April 1, 2008
Last Updated: February 16, 2009
Health Authority: Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)

Keywords provided by Maastricht University Medical Center:
exercise
muscle protein signalling
protein synthesis

ClinicalTrials.gov processed this record on July 22, 2014