Whole Blood-plasma-oral Fluid Ratios of Psychoactive Drugs and Medicines
The aim of this study is to get new information on the whole blood-plasma-oral fluid ratios of psychoactive drugs which are encountered in traffic.
Samples are taken from drivers suspected of being under the influence of drugs or medicines. The samples are analysed with immunological methods and GC-MS.
Observations from Police and a physician on impairment are combined with the results of the different bodily fluids. Observational evaluations and substance concentrations are compared.
Driving Under the Influence
|Study Design:||Observational Model: Case Control|
|Official Title:||DRUID Sub-study: Substance Concentration Ratio/Impairment|
- ratio of psychoactive drugs/medicines in whole blood-plasma-saliva and correlation to symptoms of impairment [ Time Frame: 1 year ] [ Designated as safety issue: Yes ]
- prevalence of psychoactive substances in the general driving population [ Time Frame: three years ] [ Designated as safety issue: Yes ]
Biospecimen Retention: Samples With DNA
Blood samples and oral fluid are collected for the study. However no DNA detection is done at any stage. The laboratory where samples are analysed do not analyse DNA. DNA is not relevant to this study.
|Study Start Date:||May 2008|
|Study Completion Date:||October 2011|
|Primary Completion Date:||December 2008 (Final data collection date for primary outcome measure)|
drivers of motorised vehicles suspected of being under the influence of psychoactive drugs
|National Public Health Institute|
|Principal Investigator:||Pirjo Lillsunde, Dr||National Public Health Institute, Helsinki, Finland|