Follow-up the Health Condition , Investigation of the Immuno-regulation , and the Study for Interaction of Viral Hepatitis--- Among Patients With or After Dengue Fever Infection
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Purpose
Originally test host's to understand the tracking healthily and immune change of the dengue fever in Taiwan. Blood drawing 20 c.c for liver examination, kidney and other biochemical function, analyze host immunity adjusts and controls the gene, and the reciprocation that may be produced with the virus hepatitis, besides collected 10 c.c urine at the same time. Urine check is in order to compare acute infect and infected over three month person, the change of chemical composition.
This plan expect to collect 150 healthy, 150 dengue fever infected and 150 dengue fever bleed hot or dengue fever shock disease group's patient, goal to understand health state and immunity of follow-up adjust and control the difference of the gene and the reciprocation may produce to virus hepatitis of light disease and serious disease.
| Condition | Intervention |
|---|---|
|
Dengue |
Genetic: dengue fever |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Retrospective |
| Official Title: | Follow-up the Health Condition , Investigation of the Immuno-regulation , and the Study for Interaction of Viral Hepatitis--- Among Patients With or After Dengue Fever Infection |
| Estimated Enrollment: | 450 |
| Study Start Date: | July 2007 |
| Estimated Study Completion Date: | July 2008 |
The dengue fever is an important tropical infectious disease in the south of Taiwan, cause and threaten of public health at Kaohsiung and Ping-Dong all over the years, this will cause patient's death, the default of clinical change of dengue fever, acute infect, infect influence, host immunity adjust and control, and the reciprocation of virus hepatitis, will be a very urgent in basic research.
Originally test host's to understand the tracking healthily and immune change of the dengue fever in Taiwan. Blood drawing 20 c.c for liver examination, kidney and other biochemical function, analyze host immunity adjusts and controls the gene, and the reciprocation that may be produced with the virus hepatitis, besides collected 10 c.c urine at the same time.
This plan expect to collect 150 healthy, 150 dengue fever infected and 150 dengue fever bleed hot or dengue fever shock disease group's patient, goal to understand health state and immunity of follow-up adjust and control the difference of the gene and the reciprocation may produce to virus hepatitis of light disease and serious disease.
Urine check is in order to compare acute infect and infected over three month person, the change of chemical composition. The result of study can help doctor to understand the factor of immune regulation and control of the host and health change after the dengue fever is infected with, possible reciprocation with virus hepatitis. Researchers have collect 100 dengue fever bleed hot or dengue fever shock syndrome groups of patient, it is estimated that can collect and expect the case will be counted within two years.
Eligibility| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Probability Sample |
The patients who are suspicious of dengue infection.
Inclusion Criteria:
- Clinical diagnosis of Dengue Fever
Contacts and Locations| Taiwan | |
| Kaoshing Medical University Chung-Ho Memorial Hospital | |
| Kaoshiung, Taiwan | |
| Study Director: | Jih-Jin Tsai, MD | Chung-Ho Memorial Hospital,Kaoshing Medical University |
More Information
No publications provided
| Responsible Party: | Jih Jin Tsai/Dr, Kaoshing Medical University Chung-Ho Memorial Hospital |
| ClinicalTrials.gov Identifier: | NCT00629356 History of Changes |
| Other Study ID Numbers: | KMUH-IRB-960195 |
| Study First Received: | February 26, 2008 |
| Last Updated: | June 3, 2010 |
| Health Authority: | Taiwan: Institutional Review Board |
Additional relevant MeSH terms:
|
Dengue Dengue Hemorrhagic Fever Hepatitis Arbovirus Infections Virus Diseases Flavivirus Infections |
Flaviviridae Infections RNA Virus Infections Hemorrhagic Fevers, Viral Liver Diseases Digestive System Diseases |
ClinicalTrials.gov processed this record on May 16, 2013