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Follow-up the Health Condition , Investigation of the Immuno-regulation , and the Study for Interaction of Viral Hepatitis--- Among Patients With or After Dengue Fever Infection

This study has been withdrawn prior to enrollment.
(The study had been revised and made a new application.)
Sponsor:
Information provided by:
Kaohsiung Medical University Chung-Ho Memorial Hospital
ClinicalTrials.gov Identifier:
NCT00629356
First received: February 26, 2008
Last updated: June 3, 2010
Last verified: May 2010
  Purpose

Originally test host's to understand the tracking healthily and immune change of the dengue fever in Taiwan. Blood drawing 20 c.c for liver examination, kidney and other biochemical function, analyze host immunity adjusts and controls the gene, and the reciprocation that may be produced with the virus hepatitis, besides collected 10 c.c urine at the same time. Urine check is in order to compare acute infect and infected over three month person, the change of chemical composition.

This plan expect to collect 150 healthy, 150 dengue fever infected and 150 dengue fever bleed hot or dengue fever shock disease group's patient, goal to understand health state and immunity of follow-up adjust and control the difference of the gene and the reciprocation may produce to virus hepatitis of light disease and serious disease.


Condition Intervention
Dengue
Genetic: dengue fever

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Retrospective
Official Title: Follow-up the Health Condition , Investigation of the Immuno-regulation , and the Study for Interaction of Viral Hepatitis--- Among Patients With or After Dengue Fever Infection

Resource links provided by NLM:


Further study details as provided by Kaohsiung Medical University Chung-Ho Memorial Hospital:

Estimated Enrollment: 450
Study Start Date: July 2007
Estimated Study Completion Date: July 2008
Detailed Description:

The dengue fever is an important tropical infectious disease in the south of Taiwan, cause and threaten of public health at Kaohsiung and Ping-Dong all over the years, this will cause patient's death, the default of clinical change of dengue fever, acute infect, infect influence, host immunity adjust and control, and the reciprocation of virus hepatitis, will be a very urgent in basic research.

Originally test host's to understand the tracking healthily and immune change of the dengue fever in Taiwan. Blood drawing 20 c.c for liver examination, kidney and other biochemical function, analyze host immunity adjusts and controls the gene, and the reciprocation that may be produced with the virus hepatitis, besides collected 10 c.c urine at the same time.

This plan expect to collect 150 healthy, 150 dengue fever infected and 150 dengue fever bleed hot or dengue fever shock disease group's patient, goal to understand health state and immunity of follow-up adjust and control the difference of the gene and the reciprocation may produce to virus hepatitis of light disease and serious disease.

Urine check is in order to compare acute infect and infected over three month person, the change of chemical composition. The result of study can help doctor to understand the factor of immune regulation and control of the host and health change after the dengue fever is infected with, possible reciprocation with virus hepatitis. Researchers have collect 100 dengue fever bleed hot or dengue fever shock syndrome groups of patient, it is estimated that can collect and expect the case will be counted within two years.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

The patients who are suspicious of dengue infection.

Criteria

Inclusion Criteria:

  • Clinical diagnosis of Dengue Fever
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00629356

Locations
Taiwan
Kaoshing Medical University Chung-Ho Memorial Hospital
Kaoshiung, Taiwan
Sponsors and Collaborators
Kaohsiung Medical University Chung-Ho Memorial Hospital
Investigators
Study Director: Jih-Jin Tsai, MD Chung-Ho Memorial Hospital,Kaoshing Medical University
  More Information

No publications provided

Responsible Party: Jih Jin Tsai/Dr, Kaoshing Medical University Chung-Ho Memorial Hospital
ClinicalTrials.gov Identifier: NCT00629356     History of Changes
Other Study ID Numbers: KMUH-IRB-960195
Study First Received: February 26, 2008
Last Updated: June 3, 2010
Health Authority: Taiwan: Institutional Review Board

Additional relevant MeSH terms:
Dengue
Arbovirus Infections
Flaviviridae Infections
Flavivirus Infections
Hemorrhagic Fevers, Viral
RNA Virus Infections
Virus Diseases

ClinicalTrials.gov processed this record on November 25, 2014