Homburg Cream & Sugar Study (HCS)
The purpose of this study is to prospectivly analyze the correlation of triglyceride tolerance and glucose tolerance with cardiovascular morbidity and mortality in patients with stable coronary artery disease within 18 months and to determine, whether measurement of triglyceride tolerance can discriminate patients at risk for cardiovascular events.
Coronary Artery Disease
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Prospective Investigation of the Influence of Triglyceride Tolerance on Cardiovascular Outcomes in Patients With Coronary Artery Disease|
- Parameters of triglyceride tolerance and glucose tolerance in correlation to cardiovascular events, cardiovascular mortality, total mortality. [ Time Frame: 48 months after inclusion. ] [ Designated as safety issue: No ]
- Waist-to-Hip ratio, nutrition protocol, physical activity, non-invasive endothelial function, body fat composition, other biomarkers of lipid and glucose metabolism. [ Time Frame: Directly after inclusion. ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples Without DNA
|Study Start Date:||February 2008|
|Study Completion Date:||August 2013|
|Primary Completion Date:||July 2013 (Final data collection date for primary outcome measure)|
> 500 consecutive patients with coronary artery disease fulfilling eligibility criteria.
|University Hospital Homburg / Saar - Cardiology Department|
|Homburg, Saarland, Germany, 66421|
|Principal Investigator:||Ulrich Laufs, MD||University Hospital, Saarland|