Novel Technique for Botulinum Toxin Injection to Minimize Patient Discomfort
This single blinded randomized pilot study was performed on 21 Caucasian females to determine if injections through follicular openings were less painful than traditional injections for cosmetic botulinum toxin type A injections.
|Study Design:||Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single Blind (Subject)
Primary Purpose: Supportive Care
|Official Title:||Novel Technique for Botulinum Toxin Injection to Minimize Patient Discomfort|
- Decrease pain on injection for treatment intervention assessed on a 10 point scale [ Time Frame: At time of intervention ] [ Designated as safety issue: No ]
|Study Start Date:||January 2007|
|Study Completion Date:||May 2007|
|Primary Completion Date:||May 2007 (Final data collection date for primary outcome measure)|
Drug: botulinum type a
Objective: To investigate whether injection of botulinum toxin type A is less painful if performed through follicular openings versus traditional non-specific approach.
Design: Prospective, randomized, single-blinded study.
Setting: Academic dermatology department.
Patients: A volunteer sample of twenty female patients aged 25-55 who had no prior history of botulinum toxin injection.
Intervention: Each patient received six randomized injections of botulinum toxin type A (Botox® Allergan). Two injections into the procerus muscle and two into each corrugator muscle. Three of the injections were performed through follicular openings and three were performed traditionally.
Main Outcome Measure: Patient discomfort on a 1-10 scale and direct comparison between the two injection techniques.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00628472
|United States, Michigan|
|Henry Ford Health System|
|Detroit, Michigan, United States, 48202|
|Principal Investigator:||David M Ozog, MD||Henry Ford Health System|