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VLDL-triglyceride Under Acute Hyperinsulinaemia

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Aarhus
ClinicalTrials.gov Identifier:
NCT00624104
First received: February 18, 2008
Last updated: November 4, 2011
Last verified: November 2011
History of Changes
  Purpose

The purpose of the study is to investigate and compare the lipid metabolism in lean and obese individuals. We want to investigate the effect of postprandial hyperinsulinaemia on VLDL-triglyceride metabolism


Condition Intervention
Obesity
 Dietary Supplement: Food (fat free meal)

Study Type: Observational
Official Title: VLDL-triglyceride Under Acute Hyperinsulinaemia

Resource links provided by NLM:

MedlinePlus related topics: Obesity
U.S. FDA Resources

Further study details as provided by University of Aarhus:

Primary Outcome Measures:
  • VLDL metabolism [ Time Frame: Few hours ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

specimen of muscle specimen of adipose tissue


Enrollment: 16
Study Start Date: March 2008
Study Completion Date: December 2010
Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
1
Lean male
 Dietary Supplement: Food (fat free meal)
Fat free meal (40% of REE)
2
Males with type 2 diabetes
 Dietary Supplement: Food (fat free meal)
Fat free meal (40% of REE)

  Eligibility

Ages Eligible for Study:   20 Years to 65 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Males with diabetes from departments out-patient clinic. Control group of healthyt volunteers

Criteria

Inclusion Criteria:

- Written consent

Exclusion Criteria:

  • Known diseases
  • Alcohol abuse
  • Smoker
  • Regular use of medicine
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00624104

Locations
Denmark
Department of Endocrinology M, Aarhus Hospital
Aarhus C, Denmark, 8000
Sponsors and Collaborators
University of Aarhus
  More Information

No publications provided

Responsible Party: University of Aarhus
ClinicalTrials.gov Identifier: NCT00624104     History of Changes
Other Study ID Numbers: ES-0001
Study First Received: February 18, 2008
Last Updated: November 4, 2011
Health Authority: Denmark: Danish Dataprotection Agency

Keywords provided by University of Aarhus:
VLDL
Kinetics
Hyperinsulinaemia
Obesity

Additional relevant MeSH terms:
Hyperinsulinism
Obesity
Glucose Metabolism Disorders
Metabolic Diseases
Overnutrition
 Nutrition Disorders
Overweight
Body Weight
Signs and Symptoms

ClinicalTrials.gov processed this record on May 22, 2013