Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education

This study has been completed.
Sponsor:
Collaborator:
Boston Public Schools
Information provided by:
Children's Hospital Boston
ClinicalTrials.gov Identifier:
NCT00612482
First received: January 29, 2008
Last updated: March 11, 2011
Last verified: March 2011
  Purpose

Our primary goal is to conduct a pilot study of the effects of a new potential strategy for youth substance abuse prevention - science-based drug education integrated into the high school science curriculum. Through this pilot study we propose to: (1) demonstrate that this new strategy shows promise, and (2) estimate the effect size for the intervention.


Condition Intervention Phase
Substance Abuse
Other: drug prevention curriculum
Phase 1

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Official Title: Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education: A High School Pilot Study

Further study details as provided by Children's Hospital Boston:

Primary Outcome Measures:
  • Lifetime, past 6 month and past 30 day use of substances [ Time Frame: Pre-intervention, immediate post-intervention, 6-7 month post-intervention ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Frequency and quantity of substance use [ Time Frame: Pre-intervention, immediate post-intervention, 6-7 months post-intervention ] [ Designated as safety issue: No ]
  • Knowledge about effects of substance use on the brain [ Time Frame: Pre-intervention, immediate post-intervention, 6-7 months post-intervention ] [ Designated as safety issue: No ]
  • Perceived risk of harm of substance use [ Time Frame: Pre-intervention, immediate post-intervention, 6-7 months post-intervention ] [ Designated as safety issue: No ]
  • Intention to use substances in the next 3 months [ Time Frame: Pre-intervention, immediate post-intervention, 6-7 months post-intervention ] [ Designated as safety issue: No ]

Enrollment: 225
Study Start Date: December 2006
Study Completion Date: January 2008
Primary Completion Date: January 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: 1
Participants in the "no intervention" condition will receive the usual high school science curriculum.
Experimental: 2
Participants in the "experimental" arm will receive the 5-lesson, science-based substance abuse prevention curriculum in their science classes.
Other: drug prevention curriculum
Participants in the "experimental" arm of the study will receive the 5-lesson, science-based drug prevention curriculum in their science classes.

Detailed Description:

NIDA, in recent years, has put resources into summarizing and synthesizing cutting-edge medical and basic science research discoveries about the short-term and long-term effects of drug use on the developing brain. One outcome of this results was the production of a science-based drug education program entitled "The Brain: Understanding Neurobiology Through the Study of Addiction." This is a 5-lesson module for high school science classes that teaches about brain structure and function, how drugs affect and change the biology and chemistry of the brain, how addiction occurs in the brain, and that addiction is a chronic, recurring disease. However, the effect of receipt of this program on students' substance use knowledge, attitudes, perceived risk of harm, and behavior has not been systematically evaluated to date.

The specific aims of this project are:

  1. To evaluate the effects of receipt of the curriculum on specific cognitive contributors to substance use including a)students' knowledge about the short- and long-term effects of substance use on the brain; b)perceived risk of harm from substance use; and c)intention to use substances in the next 3 months.
  2. To evaluate the effects of the intervention on actual substance use behavior. We hypothesize that the effectiveness of this approach may be modified by the students' level of prior and current substance use, with the effect being stronger among those who have not already initiated use, or among those who have very low use. Therefore, we will specifically examine whether the intervention a)prevents substance use initiation among students who had no previous use, b)stops use among students with low lifetime use, and c) reduces use among those with higher levels of use.
  Eligibility

Ages Eligible for Study:   14 Years to 19 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Student in 9th/10th/11th grade science classes at Fenway High School at start of study or student in 11th grade science classes at Boston Arts Academy at start of study
  • Parental permission to participate

Exclusion Criteria:

  • No parental permission to participate
  • Unable to read English
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00612482

Locations
United States, Massachusetts
Children's Hospital Boston
Boston, Massachusetts, United States, 02115
Sponsors and Collaborators
Children's Hospital Boston
Boston Public Schools
Investigators
Principal Investigator: Sion Kim Harris, PhD Children's Hospital Boston
  More Information

Additional Information:
No publications provided

Responsible Party: Sion Kim Harris, Children's Hospital Boston
ClinicalTrials.gov Identifier: NCT00612482     History of Changes
Other Study ID Numbers: 06120537
Study First Received: January 29, 2008
Last Updated: March 11, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by Children's Hospital Boston:
Substance abuse

ClinicalTrials.gov processed this record on September 16, 2014