Improving Posthospital Medication Management of Older Adults Through Health IT
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Purpose
The incidence of drug-induced injury is high in the ambulatory geriatric population and is increased for elders upon transition from the hospital to the ambulatory setting. In this application, we describe an effort to build on our extensive experience in medication safety and HIT-based medication management to respond to the AHRQ RFA entitled Ambulatory Safety and Quality Program: Improving Quality through Clinician Use of Health IT (RFA-HS-07-006). In this study, we propose to develop and evaluate the value of an enhanced, HIT-based transitional care intervention superimposed on the ambulatory electronic medical record (EMR) to improve the quality and safety of medication management, focusing particularly on the transition from the inpatient to the ambulatory setting for older adults with multiple comorbid conditions who are prescribed high risk medications. We propose a randomized controlled trial of a HIT-based transitional care intervention with enhanced medication and therapeutic monitoring alerts to improve the quality and safety of patient monitoring and medication management. We postulate that the efficient and coordinated delivery of actionable health information to the clinician via use of HIT in the ambulatory setting can improve medication safety for the growing geriatric population. The specific aims for this study are to evaluate, among a population of older adults discharged from the hospital, the impact of an enhanced discharge information system initiated upon transition to the ambulatory setting: (1) on the rate of follow-up by an outpatient provider within 14 days of hospital discharge; (2) on the prevalence of appropriate monitoring for selected high risk medications at 30 days from the time of hospital discharge; (3) on the incidence of adverse drug events (ADEs) 30 days after discharge; and (4) on the rate of emergency department visits and hospital readmission within 30 days of discharge. A secondary aim for this study is to determine costs directly related to the development and installation of the HIT-based transitional care intervention. This research allows for the examination of an integrated HIT intervention on the quality of follow-up, outpatient clinician workflow, occurrence of ADEs, and health care utilization to gain insights into the effective use of clinical alerts and coordinated delivery of actionable information to outpatient clinicians in the management of ambulatory elderly patients subsequent to hospital discharge.
| Condition | Intervention |
|---|---|
|
Adverse Outcomes Post-hospital Discharge |
Other: Electronic delivery of enhanced discharge information to the ambulatory physician |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single Blind (Outcomes Assessor) Primary Purpose: Health Services Research |
| Official Title: | Improving Posthospital Medication Management of Older Adults Through Health IT |
- rate of follow-up to an outpatient provider within 14 days of hospital discharge. [ Time Frame: 1 year 3 months ] [ Designated as safety issue: Yes ]
- prevalence of appropriate monitoring for selected high risk medications at 30 days from the time of hospital discharge. [ Time Frame: 1 year 3 months ] [ Designated as safety issue: Yes ]
- incidence of adverse drug events (ADEs) 45 days after discharge. [ Time Frame: 1 year 3 months ] [ Designated as safety issue: Yes ]
- rate of hospital readmission and emergency department (ED) within 30 days of discharge. [ Time Frame: 1 year 3 months ] [ Designated as safety issue: No ]
- assess whether a HIT-based transitional care intervention is more effective in subgroups of patients (by level of comorbidity, number of medications, and use of specific high risk medications) [ Time Frame: 1 year 3 months ] [ Designated as safety issue: No ]
- determine costs directly related to the development and installation of the HIT-based transitional care intervention. [ Time Frame: 3 years ] [ Designated as safety issue: No ]
| Estimated Enrollment: | 5000 |
| Study Start Date: | August 2010 |
| Estimated Study Completion Date: | November 2013 |
| Primary Completion Date: | June 2012 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Experimental: I
Intervention Group - (receive intervention) randomized at patient level - includes all health plan members, aged 65+, hospitalized at the study site hospital and discharged to an outpatient health plan clinic provider.
|
Other: Electronic delivery of enhanced discharge information to the ambulatory physician
Follow-up appointment needs/plans
Other Name: HIT
Other: Electronic delivery of enhanced discharge information to the ambulatory physician
Laboratory follow-up needs
Other Name: HIT
Other: Electronic delivery of enhanced discharge information to the ambulatory physician
New medications
Other Name: HIT
|
|
No Intervention: C
Control Group - (do not receive intervention) randomized at patient level - includes all health plan members, aged 65+, hospitalized at the study site hospital and discharged to an outpatient health plan clinic provider.
|
Eligibility| Ages Eligible for Study: | 65 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- 65+ years old, member of the study site health plan, hospitalized at the study site hospital, discharged to an outpatient provider at the study site health plan clinic
Exclusion Criteria:
- does not meet inclusion criteria
Contacts and Locations| United States, Massachusetts | |
| St Vincent's Hospital | |
| Worcester, Massachusetts, United States, 01608 | |
| Principal Investigator: | Jerry H Gurwitz, MD | Meyers Primary Care Institute/University of Massachusetts Medical School |
More Information
No publications provided
| Responsible Party: | Jerry Gurwitz, Chief, Division of Geriatric Medicine, University of Massachusetts, Worcester |
| ClinicalTrials.gov Identifier: | NCT00611091 History of Changes |
| Other Study ID Numbers: | 12603, 1R18HS017203 |
| Study First Received: | January 25, 2008 |
| Last Updated: | March 29, 2013 |
| Health Authority: | United States: Institutional Review Board |
ClinicalTrials.gov processed this record on May 23, 2013