Environmental Pollutants and the Risk of Soft Tissue Sarcoma: A Pilot Study

This study has been completed.
Sponsor:
Information provided by:
Memorial Sloan-Kettering Cancer Center
ClinicalTrials.gov Identifier:
NCT00611078
First received: January 25, 2008
Last updated: January 19, 2011
Last verified: January 2011
  Purpose

The purpose of this study is to assess the feasibility of conducting a large hospital based case control study of the role of dioxins and dioxinlike polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs).


Condition
Soft Tissue Sarcoma

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Environmental Pollutants and the Risk of Soft Tissue Sarcoma: A Pilot Study

Resource links provided by NLM:


Further study details as provided by Memorial Sloan-Kettering Cancer Center:

Primary Outcome Measures:
  • enrollment of 60 participants [ Time Frame: Conclusion of the study ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

blood, adipose tissue


Enrollment: 56
Study Start Date: September 2004
Study Completion Date: January 2011
Primary Completion Date: January 2011 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years to 79 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Patients with Soft Tissue Sarcoma at Memorial Sloan Kettering Cancer Center.

Criteria

Inclusion Criteria:

  • Patients with Soft tissue sarcoma at MSKCC are eligible for this study if they meet the following criteria:
  • Between 18 and 79 years of age
  • were diagnosed within the previous 6 months with primary soft tissue sarcoma of one of the following histologic subtypes: liposarcoma, leiomyoscaroma, MFH, or synovial sarcoma
  • are enrolled in protocol 02-060 ("Novel Biochemical and Molecularr Determinants for Soft Tissue Sarcoma"; PI, Dr. Samuel Singer)
  • controls will be eligibile for this study if they meet the following criteria
  • are b/w 18-79 years of age
  • have no prior history of cancer (other than non melanoma skin cancer)

Exclusion Criteria:

  • Individuals will be excluded if they
  • are unable to sign informed consent for medical or other reasons
  • do not speak english
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00611078

Locations
United States, New York
Memorial Sloan-Kettering Cancer Center
New York, New York, United States, 10021
Sponsors and Collaborators
Memorial Sloan-Kettering Cancer Center
Investigators
Principal Investigator: Lawrence Engel, Ph.D. Memorial Sloan-Kettering Cancer Center
  More Information

No publications provided

Responsible Party: Engel, Lawrence Stuart, PhD, Memorial Sloan-Kettering Cancer Center
ClinicalTrials.gov Identifier: NCT00611078     History of Changes
Other Study ID Numbers: 04-088
Study First Received: January 25, 2008
Last Updated: January 19, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by Memorial Sloan-Kettering Cancer Center:
Soft Tissue Sarcoma
environment
pollutants
04-088

Additional relevant MeSH terms:
Sarcoma
Neoplasms, Connective and Soft Tissue
Neoplasms by Histologic Type
Neoplasms

ClinicalTrials.gov processed this record on April 17, 2014