Balanced Volume Replacement Therapy With Ringer's Acetate Solution in Burn Injury (VoLTRAB)
This observational study compares the influence of Ringer's Lactate solution and Ringer's Acetate solution on organ function scores following severe burn injury.
Severe Burn Injury
|Study Design:||Observational Model: Cohort|
|Official Title:||Balanced Volume Replacement Therapy With Ringer's Acetate Solution in Burn Injury|
- Change of SOFA-score from day 3 to day 7 after severe burn injury [ Time Frame: day3, day7, day28, day60 ] [ Designated as safety issue: No ]
- Changes in electrolyte-balance [ Time Frame: day3, day7, day28 ] [ Designated as safety issue: No ]
|Study Start Date:||December 2007|
|Study Completion Date:||December 2010|
|Primary Completion Date:||November 2010 (Final data collection date for primary outcome measure)|
Historical group: patients treated with Ringer's Lactate solution after severe burn injury
Actual group: patients treated with Ringer's Acetate solution after severe burn injury
In the early period following severe burn injury volume replacement with high amounts of crystalloids is necessary. In this study we compare the organ function scores of a historical patient group, treated with Ringer's Lactate solution, with an actual patient population, treated with Ringer's Acetate solution.